rs56116178
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
smoking initiation
Saunders GRB et al. “Genetic diversity fuels gene discovery for tobacco and alcohol use.” Nature 612(7941):720-724 (2022)
Allele G
OR 0.01
p 1.0e-16
N 3,382,012
Large GWAS
European, East Asian, Hispanic or Latin American, African unspecified
nicotine dependence
Quach BC et al. “Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits.” Nature Communications 11(1):5562 (2020)
Allele A
OR 0.04
p 2.0e-13
N 58,000
Large GWAS
multi-ancestry
cigarettes per day measurement
Koskeridis F et al. “Pleiotropic genetic architecture and novel loci for C-reactive protein levels.” Nature Communications 13(1):6939 (2022)
Allele A
OR 0.03
p 6.0e-12
N 337,334
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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