rs56228609

This is a upstream gene variant variant.

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GWAS Catalog Trait Associations (22)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

protein measurement

Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.20
p 6.0e-44
N 10,708
Large GWAS
European

interferon gamma receptor 2 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.04
p 2.0e-26
N 47,745
Large GWAS
European

high density lipoprotein cholesterol measurement

Sohail M et al. “Mexican Biobank advances population and medical genomics of diverse ancestries.” Nature 622(7984):775-783 (2023)
Allele C
OR 0.20
p 3.0e-24
N 4,484
Large GWAS
Hispanic or Latin American

protein FAM177A1 measurement

Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele T
OR 0.13
p 4.0e-19
N 10,708
Large GWAS
European

neurogenic locus notch homolog protein 3 measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.04
p 5.0e-15
N 47,745
Large GWAS
European

1,2-dipalmitoyl-GPC (16:0/16:0) measurement

Surendran P et al. “Rare and common genetic determinants of metabolic individuality and their effects on human health.” Nature Medicine 28(11):2321-2332 (2022)
Allele T
OR 0.08
p 7.0e-14
N 14,296
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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