rs6671847

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

systemic lupus erythematosus

Bentham J et al. “Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.” Nature Genetics 47(12):1457-1464 (2015)

Allele A

OR 1.20

p 1.0e-12

N 14,267

Large GWAS

European

inflammatory bowel disease

Wu Y et al. “GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression.” Nature Communications 12(1):1146 (2021)

Allele G

OR 1.13

p 2.0e-12

N 456,327

Large GWAS

European

blood protein amount

Orrù V et al. “Complex genetic signatures in immune cells underlie autoimmunity and inform therapy.” Nature Genetics 52(10):1036-1045 (2020)

Allele A

OR 0.18

p 5.0e-11

N 3,618

Large GWAS

European

mucocutaneous lymph node syndrome

Hoggart C et al. “Identification of novel locus associated with coronary artery aneurysms and validation of loci for susceptibility to Kawasaki disease.” European Journal of Human Genetics : Ejhg 29(12):1734-1744 (2021)

Allele A

OR 0.70

p 3.0e-9

N 6,501

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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