rs71559014

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

low density lipoprotein cholesterol measurement

Klarin D et al. “Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.” Nature Genetics 50(11):1514-1523 (2018)

Allele A

OR 0.04

p 1.0e-12

N 297,626

Major Consortium StudyLarge GWAS

multi-ancestry

thyroxine level

Rand SA et al. “Genome-wide association study and polygenic risk prediction of hypothyroidism.” Nature Genetics 57(12):3007-3015 (2025)

Allele G

OR 0.04

p 8.0e-10

N 191,449

Large GWAS

European

total cholesterol measurement

Klarin D et al. “Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.” Nature Genetics 50(11):1514-1523 (2018)

Allele A

OR 0.03

p 4.0e-9

N 297,626

Major Consortium StudyLarge GWAS

multi-ancestry

total iron binding capacity

Raffield LM et al. “Genome-wide association study of iron traits and relation to diabetes in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL): potential genomic intersection of iron and glucose regulation?” Human Molecular Genetics 26(10):1966-1978 (2017)

Allele A

OR 0.30

p 5.0e-8

N 12,586

Large GWAS

Hispanic or Latin American

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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