rs72660908

This is a intron variant variant in the RSRP1 gene.

GWAS Catalog Trait Associations (14)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

intercellular adhesion molecule 4 measurement

Pietzner M et al. Mapping the proteo-genomic convergence of human diseases. Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele C
OR 0.62
p
N 10,708
Large GWAS
European
Sun BB et al. Genomic atlas of the human plasma proteome. Nature 558(7708):73-79 (2018)
Allele C
OR
β 0.620
p 5.0e-159
N 3,301
Large GWAS
European

platelet count

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.05
p 1.0e-60
N 406,601
Major Consortium StudyLarge GWAS
European

mean corpuscular hemoglobin

Allele G
OR 0.02
p 6.0e-24
N 394,642
Large GWAS
European

erythrocyte volume

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.03
p 3.0e-19
N 583,955
Major Consortium StudyLarge GWAS
multi-ancestry

total lipids in very large HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.01
p 7.0e-16
N 450,015
Large GWAS
multi-ancestry

Red cell distribution width

Vuckovic D et al. The Polygenic and Monogenic Basis of Blood Traits and Diseases. Cell 182(5):1214-1231.e11 (2020)
Allele G
OR 0.03
p 4.0e-15
N 408,112
Large GWAS
European

phospholipids in very large HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.01
p 3.0e-14
N 450,015
Large GWAS
multi-ancestry

concentration of large HDL particles measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.01
p 2.0e-13
N 450,015
Large GWAS
multi-ancestry

free cholesterol in large HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.01
p 4.0e-13
N 450,015
Large GWAS
multi-ancestry

total lipids in large HDL

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele G
OR 0.01
p 8.0e-11
N 450,015
Large GWAS
multi-ancestry

About RSRP1

Involved in spliceosomal complex assembly. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

View all RSRP1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…