rs753312276
This variant is located in the TMEM260 gene.
▶GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (2)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
inflammatory bowel disease
Beecham AH et al. “Genomic Insights Into Inflammatory Bowel Disease in United States Hispanic Participants: An Ancestry-Focused Study.” Gastroenterology (2026)
Allele A
OR 10.04
p 9.0e-9
N 6,669
Large GWAS
Hispanic or Latin American
Crohn's disease
Beecham AH et al. “Genomic Insights Into Inflammatory Bowel Disease in United States Hispanic Participants: An Ancestry-Focused Study.” Gastroenterology (2026)
Allele A
OR 11.60
p 2.0e-8
N 5,962
Large GWAS
Hispanic or Latin American
About TMEM260
Enables dolichyl-phosphate-mannose-protein mannosyltransferase activity. Involved in protein maturation. Is active in endoplasmic reticulum membrane. Implicated in T-cell non-Hodgkin lymphoma; non-Hodgkin lymphoma; and stomach cancer. [provided by Alliance of Genome Resources, Jul 2025]
View all TMEM260 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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