rs75426652
This is a protein-altering variant in the LHPP gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
spina bifida
Tindula G et al. “Genome-wide analysis of spina bifida risk variants in a case-control study from Bangladesh.” Birth Defects Research 116(3):e2331 (2024)
Allele A
OR —
p 7.0e-14
N 128
Small GWAS
South Asian
About LHPP
Enables inorganic diphosphate phosphatase activity and protein homodimerization activity. Involved in phosphate-containing compound metabolic process. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Jul 2025]
View all LHPP variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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