Trait
SNPs associated with Spina bifida
4 genetic variants across 3 genes have been associated with Spina bifida in published research. Key genes include ASB2, LHPP, MTRR.
Associated variants4 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs75426652 | LHPP | GWAS association (p=7.0e-14) | Small GWAS |
| rs45580033 | ASB2 | GWAS association (p=4.0e-10) | Small GWAS |
| rs10380 | MTRR | Increased spina bifida risk | Preliminary work |
| rs162036 | MTRR | Increased risk of spina bifida | Preliminary work |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.