rs77100309
This is a intron variant variant in the JDP2 gene.
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
basal cell carcinoma
Seviiri M et al. “A multi-phenotype analysis reveals 19 susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinoma.” Nature Communications 13(1):7650 (2022)
Allele A
OR —
p 3.0e-28
N 307,684
Large GWAS
European
keratinocyte carcinoma
Liyanage UE et al. “Combined analysis of keratinocyte cancers identifies novel genome-wide loci.” Human Molecular Genetics 28(18):3148-3160 (2019)
Allele A
OR 1.10
p 2.0e-8
N 358,840
Large GWAS
European
skin neoplasm
Sakaue S et al. “A cross-population atlas of genetic associations for 220 human phenotypes.” Nature Genetics 53(10):1415-1424 (2021)
Allele A
OR 0.10
p 3.0e-8
N 670,929
Large GWAS
multi-ancestry
About JDP2
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific double-stranded DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. [provided by Alliance of Genome Resources, Jul 2025]
View all JDP2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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