rs77583790
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
systemic scleroderma
Mayes MD et al. “Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis.” American Journal of Human Genetics 94(1):47-61 (2014)
Allele A
OR 2.57
p 1.0e-11
N 5,299
Large GWAS
European
limited scleroderma
Mayes MD et al. “Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis.” American Journal of Human Genetics 94(1):47-61 (2014)
Allele A
OR 2.81
p 2.0e-11
N 4,593
Large GWAS
European
systemic lupus erythematosus
Bentham J et al. “Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.” Nature Genetics 47(12):1457-1464 (2015)
Allele A
OR 2.15
p 6.0e-11
N 14,267
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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