rs77641763
▶GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
restless legs syndrome
Schormair B et al. “Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction.” Nature Genetics 56(6):1090-1099 (2024)
Allele T
OR 0.07
p 2.0e-24
N 1,663,113
Large GWAS
European
body mass index
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.05
p 7.0e-15
N 607,391
Major Consortium StudyLarge GWAS
multi-ancestry
body weight
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele C
OR 0.05
p 2.0e-13
N 609,198
Major Consortium StudyLarge GWAS
multi-ancestry
circadian rhythm
Jones SE et al. “Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.” Plos Genetics 12(8):e1006125 (2016)
Allele C
OR 0.04
p 2.0e-12
N 127,898
Large GWAS
European
chronotype measurement
Jansen PR et al. “Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.” Nature Genetics 51(3):394-403 (2019)
Allele T
OR 0.02
p 2.0e-11
N 385,949
Large GWAS
European
suicidal ideation
Ashley-Koch AE et al. “Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program.” Plos Genetics 19(3):e1010623 (2023)
Allele T
OR 0.06
p 4.0e-10
N 612,381
Major Consortium StudyLarge GWAS
multi-ancestry
suicidal ideation, suicide behaviour
Kimbrel NA et al. “Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.” Jama Psychiatry 80(2):135-145 (2023)
Allele T
OR —
p 2.0e-9
N 633,778
Large GWAS
multi-ancestry
post-traumatic stress disorder symptom measurement
Stein MB et al. “Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program.” Nature Genetics 53(2):174-184 (2021)
Allele T
OR 0.43
p 9.0e-9
N 237,725
Major Consortium StudyLarge GWAS
multi-ancestry
insomnia measurement
Jansen PR et al. “Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.” Nature Genetics 51(3):394-403 (2019)
Allele T
OR 1.08
p 2.0e-11
N 1,331,010
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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