rs7786102

GWAS Catalog Trait Associations (10)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

total lipids in large HDL

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.03
p 6.0e-35
N 450,015
Large GWAS
multi-ancestry

polyunsaturated fatty acids to monounsaturated fatty acids ratio

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 1.0e-23
N 450,015
Large GWAS
multi-ancestry

saturated fatty acids to total fatty acids percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 1.0e-23
N 450,015
Large GWAS
multi-ancestry

LDL particle size

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 1.0e-17
N 450,015
Large GWAS
multi-ancestry

triglyceride measurement

Koskeridis F et al. Pleiotropic genetic architecture and novel loci for C-reactive protein levels. Nature Communications 13(1):6939 (2022)
Allele A
OR 0.02
p 8.0e-17
N 361,194
Large GWAS
European

fatty acid amount

Allele G
OR
p 9.0e-13
N 239,268
Large GWAS
European

valine measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 5.0e-12
N 450,015
Large GWAS
multi-ancestry

high density lipoprotein cholesterol measurement

Koskeridis F et al. Pleiotropic genetic architecture and novel loci for C-reactive protein levels. Nature Communications 13(1):6939 (2022)
Allele A
OR 0.02
p 2.0e-8
N 361,194
Large GWAS
European

polyunsaturated fatty acids to total fatty acids percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 7.0e-20
N 450,015
Large GWAS
multi-ancestry

triglyceride:HDL cholesterol ratio

Allele G
OR 0.02
p 4.0e-8
N 185,749
Major Consortium StudyLarge GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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