rs7903456
This is a intron variant variant in the SHLD2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
gout
Nakayama A et al. “GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.” Annals of the Rheumatic Diseases 76(5):869-877 (2017)
Allele A
OR 1.34
p 4.0e-8
N 1,832
Large GWAS
East Asian
About SHLD2
Involved in negative regulation of double-strand break repair via homologous recombination; positive regulation of double-strand break repair via nonhomologous end joining; and positive regulation of isotype switching. Located in actin cytoskeleton; nucleoplasm; and site of double-strand break. [provided by Alliance of Genome Resources, Jul 2025]
View all SHLD2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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