rs8024538
This variant is located in the ALPK3 gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
myoglobin measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele T
OR 0.03
p 4.0e-12
N 47,745
Large GWAS
European
platelet count
Jee YH et al. “Genome-wide association studies in a large Korean cohort identify quantitative trait loci for 36 traits and illuminate their genetic architectures.” Nature Communications 16(1):4935 (2025)
Allele A
OR 0.01
p 9.0e-12
N 928,679
Large GWAS
multi-ancestry
QT interval
Hoffmann TJ et al. “A large genome-wide association study of QT interval length utilizing electronic health records.” Genetics 222(4) (2022)
Allele A
OR 0.63
p 2.0e-9
N 76,995
Large GWAS
multi-ancestry
cardiac troponin I measurement
Moksnes MR et al. “Genome-wide association study of cardiac troponin I in the general population.” Human Molecular Genetics 30(21):2027-2039 (2021)
Allele T
OR 0.03
p 6.0e-9
N 48,115
Large GWAS
European
About ALPK3
Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in cardiac muscle cell development. Predicted to be active in nucleus. Implicated in hypertrophic cardiomyopathy 27. [provided by Alliance of Genome Resources, Jul 2025]
View all ALPK3 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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