rs8103315

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GWAS Catalog Trait Associations (4)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

C-reactive protein measurement

Koskeridis F et al. “Pleiotropic genetic architecture and novel loci for C-reactive protein levels.” Nature Communications 13(1):6939 (2022)

Allele A

OR 0.03

p 1.0e-26

N 575,531

Large GWAS

European

platelet-activating factor acetylhydrolase measurement

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)

Allele A

OR 0.07

p 4.0e-17

N 47,745

Large GWAS

European

Alzheimer disease, family history of Alzheimer’s disease

Willett JDS et al. “Identification of 16 novel Alzheimer's disease loci using multi-ancestry meta-analyses.” Alzheimer's & Dementia : the Journal of the Alzheimer's Association 21(2):e14592 (2025)

Allele A

OR —

p 3.0e-15

N 404,467

Large GWAS

multi-ancestry

Alzheimer disease

Wang H et al. “Similar Genetic Architecture of Alzheimer's Disease and Differential APOE Effect Between Sexes.” Frontiers in Aging Neuroscience 13:674318 (2021)

Allele A

OR 1.35

p 8.0e-11

N 12,772

Large GWAS

European

Allele A

OR —

p 3.0e-8

N 27,907

Large GWAS

European, African unspecified, Hispanic or Latin American, Asian unspecified, NR

This variant is in our database but has no known associations or PRS memberships yet.

rs8103315

GWAS Catalog Trait Associations (4)

C-reactive protein measurement

platelet-activating factor acetylhydrolase measurement

Alzheimer disease, family history of Alzheimer’s disease

Alzheimer disease

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