rs910187

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GWAS Catalog Trait Associations (9)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

insomnia

Watanabe K et al. “Genome-wide meta-analysis of insomnia prioritizes genes associated with metabolic and psychiatric pathways.” Nature Genetics 54(8):1125-1132 (2022)
Allele A
OR 0.01
p 2.0e-16
N 2,365,010
Meta-analysisLarge GWAS
European

wellbeing measurement

Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)
Allele A
OR 0.01
p 2.0e-11
N 2,083,151
Large GWAS
European
Kim S et al. “Shared genetic architectures of subjective well-being in East Asian and European ancestry populations.” Nature Human Behaviour 6(7):1014-1026 (2022)
Allele A
OR 0.01
p 2.0e-10
N 674,095
Large GWAS
multi-ancestry

major depressive disorder

Als TD et al. “Depression pathophysiology, risk prediction of recurrence and comorbid psychiatric disorders using genome-wide analyses.” Nature Medicine 29(7):1832-1844 (2023)
Allele G
OR 0.02
p 6.0e-11
N 1,349,887
Large GWAS
European
Meng X et al. “Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference.” Nature Genetics 56(2):222-233 (2024)
Allele G
OR 0.02
p 4.0e-8
N 1,820,689
Large GWAS
multi-ancestry

migraine disorder

Hautakangas H et al. “Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles.” Nature Genetics 54(2):152-160 (2022)
Allele G
OR 1.04
p 1.0e-10
N 873,341
Large GWAS
European

daytime rest measurement

Dashti HS et al. “Genetic determinants of daytime napping and effects on cardiometabolic health.” Nature Communications 12(1):900 (2021)
Allele G
OR 0.01
p 3.0e-10
N 452,633
Large GWAS
European

neuroticism measurement

Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)
Allele A
OR 0.01
p 3.0e-10
N 523,783
Large GWAS
European

depressive symptom measurement

Baselmans BML et al. “Multivariate genome-wide analyses of the well-being spectrum.” Nature Genetics 51(3):445-451 (2019)
Allele A
OR 0.01
p 4.0e-10
N 1,067,913
Large GWAS
European

insomnia measurement

Jansen PR et al. “Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways.” Nature Genetics 51(3):394-403 (2019)
Allele G
OR 1.04
p 2.0e-8
N 1,331,010
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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