rs9298506

This is a regulatory region variant variant.

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GWAS Catalog Trait Associations (8)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

total cholesterol measurement

Graham SE et al. “The power of genetic diversity in genome-wide association studies of lipids.” Nature 600(7890):675-679 (2021)
Allele G
OR 0.02
p 8.0e-36
N 1,320,016
Large GWAS
European

low density lipoprotein cholesterol measurement

Graham SE et al. “The power of genetic diversity in genome-wide association studies of lipids.” Nature 600(7890):675-679 (2021)
Allele G
OR 0.02
p 2.0e-35
N 1,320,016
Large GWAS
European
Richardson TG et al. “Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.” Plos Medicine 17(3):e1003062 (2020)
Allele G
OR 0.02
p 3.0e-13
N 440,546
Large GWAS
European
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.02
p 3.0e-18
N 394,642
Large GWAS
European

non-high density lipoprotein cholesterol measurement

Graham SE et al. “The power of genetic diversity in genome-wide association studies of lipids.” Nature 600(7890):675-679 (2021)
Allele G
OR 0.03
p 5.0e-34
N 1,320,016
Large GWAS
European

body height

Yengo L et al. “A saturated map of common genetic variants associated with human height.” Nature 610(7933):704-712 (2022)
Allele G
OR 0.01
p 4.0e-29
N 5,314,291
Large GWAS
European, Hispanic or Latin American, East Asian, African unspecified, South Asian

sialic acid-binding Ig-like lectin 9 amount

Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.03
p 3.0e-13
N 47,745
Large GWAS
European

brain aneurysm

Yasuno K et al. “Genome-wide association study of intracranial aneurysm identifies three new risk loci.” Nature Genetics 42(5):420-5 (2010)
Allele A
OR 1.28
p 1.0e-12
N 15,295
Large GWAS
multi-ancestry
Bilguvar K et al. “Susceptibility loci for intracranial aneurysm in European and Japanese populations.” Nature Genetics 40(12):1472-7 (2008)
Allele A
OR 1.35
p 2.0e-9
N 7,856
Large GWAS
multi-ancestry

coronary artery disease

Tcheandjieu C et al. “Large-scale genome-wide association study of coronary artery disease in genetically diverse populations.” Nature Medicine 28(8):1679-1692 (2022)
Allele A
OR 0.03
p 3.0e-8
N 1,077,578
Large GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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