Trait
SNPs associated with Degeneration Of Macula And Posterior Pole
18 genetic variants across 11 genes have been associated with Degeneration Of Macula And Posterior Pole in published research. Key genes include C3, C9, CD46.
Associated variants18 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1329424 | CFH | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs61871744 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs11200630 | LOC105378525 | GWAS association (p=2.0e-272) | Major Consortium Study |
| rs429608 | SKIV2L | GWAS association (p=1.0e-91) | Major Consortium Study |
| rs2230199 | C3 | GWAS association (p=3.0e-57) | Major Consortium Study |
| rs3816117 | CETP | GWAS association (p=3.0e-24) | Major Consortium Study |
| rs11118580 | CD46 | GWAS association (p=8.0e-21) | Major Consortium Study |
| rs6657476 | CD46 | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs1667392 | HERC2 | GWAS association (p=9.0e-20) | Major Consortium Study |
| rs3138141 | RDH5 | GWAS association (p=5.0e-19) | Major Consortium Study |
| rs141853578 | CFI | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs34882957 | C9 | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs579745 | CFH | GWAS association (p=4.0e-17) | Major Consortium Study |
| rs1532624 | CETP | GWAS association (p=1.0e-16) | Major Consortium Study |
| rs7758685 | — | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs12438302 | HERC2 | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs2284665 | HTRA1 | GWAS association (p=6.0e-13) | Major Consortium Study |
| rs130649 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.