Trait
SNPs associated with Familial Lipoprotein Lipase Deficiency
30 genetic variants across 16 genes have been associated with Familial Lipoprotein Lipase Deficiency in published research. Key genes include AFF1, ANGPTL4, APOA5.
Associated variants30 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs964184 | APOA5 | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs75627662 | — | GWAS association (p=2.0e-138) | Major Consortium Study |
| rs3208305 | LPL | GWAS association (p=3.0e-129) | Major Consortium Study |
| rs1260326 | GCKR | GWAS association (p=3.0e-92) | Major Consortium Study |
| rs2980888 | — | GWAS association (p=1.0e-65) | Major Consortium Study |
| rs2954038 | — | GWAS association (p=6.0e-62) | Major Consortium Study |
| rs12740374 | CELSR2 | GWAS association (p=7.0e-45) | Major Consortium Study |
| rs10789118 | DOCK7 | GWAS association (p=1.0e-39) | Major Consortium Study |
| rs72836561 | — | GWAS association (p=4.0e-38) | Major Consortium Study |
| rs174535 | MYRF | GWAS association (p=2.0e-36) | Major Consortium Study |
| rs174564 | FADS2 | GWAS association (p=5.0e-34) | Major Consortium Study |
| rs11076175 | CETP | GWAS association (p=5.0e-32) | Major Consortium Study |
| rs10889356 | DOCK7 | GWAS association (p=6.0e-32) | Major Consortium Study |
| rs116843064 | ANGPTL4 | GWAS association (p=2.0e-28) | Major Consortium Study |
| rs2144300 | GALNT2 | GWAS association (p=4.0e-27) | Major Consortium Study |
| rs11967262 | — | GWAS association (p=2.0e-21) | Major Consortium Study |
| rs1801689 | APOH | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs138294113 | — | GWAS association (p=3.0e-17) | Major Consortium Study |
| rs11787313 | — | GWAS association (p=9.0e-15) | Major Consortium Study |
| rs2972156 | — | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs11591147 | PCSK9 | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs2943648 | — | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs342469 | AFF1 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs13107325 | SLC39A8 | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs7898735 | — | GWAS association (p=6.0e-12) | Major Consortium Study |
| rs28588745 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs35529421 | DOCK7 | GWAS association (p=2.0e-11) | Major Consortium Study |
| rs12453598 | PGS1 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs200362396 | — | GWAS association (p=6.0e-13) | Major Consortium Study |
| rs33951980 | MLXIPL | GWAS association (p=3.0e-48) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.