Trait
SNPs associated with Primary Angle Closure Glaucoma
11 genetic variants across 10 genes have been associated with Primary Angle Closure Glaucoma in published research. Key genes include C10orf53, COL11A1, EPDR1.
Associated variants11 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs374522377 | PCMTD1 | GWAS association (p=7.0e-18) | Major Consortium Study |
| rs7744813 | KCNQ5 | GWAS association (p=7.0e-14) | Major Consortium Study |
| rs746970 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs3753841 | COL11A1 | GWAS association (p=1.0e-23) | Large GWAS |
| rs1258267 | C10orf53 | GWAS association (p=3.0e-16) | Large GWAS |
| rs1015213 | LOC124901944 | GWAS association (p=5.0e-16) | Large GWAS |
| rs3816415 | EPDR1 | GWAS association (p=6.0e-15) | Large GWAS |
| rs736893 | GLIS3 | GWAS association (p=1.0e-14) | Large GWAS |
| rs3739821 | FAM102A | GWAS association (p=8.0e-12) | Large GWAS |
| rs7494379 | FERMT2 | GWAS association (p=3.0e-11) | Large GWAS |
| rs11024102 | PLEKHA7 | GWAS association (p=8.0e-19) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.