Trait
SNPs associated with Raynaud disease
13 genetic variants across 4 genes have been associated with Raynaud disease in published research. Key genes include ACVR2A, ARVCF, NOS3.
Associated variants13 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs563299396 | — | GWAS association (p=5.0e-13) | Major Consortium Study |
| rs376381515 | ARVCF | GWAS association (p=4.0e-12) | Major Consortium Study |
| rs11195425 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs7090046 | — | GWAS association (p=4.0e-47) | Large GWAS |
| rs7706161 | — | GWAS association (p=4.0e-26) | Large GWAS |
| rs3130968 | — | GWAS association (p=7.0e-16) | Large GWAS |
| rs12653958 | — | GWAS association (p=5.0e-13) | Large GWAS |
| rs3918226 | NOS3 | GWAS association (p=1.0e-09) | Large GWAS |
| rs3094013 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs7559925 | ACVR2A | GWAS association (p=3.0e-08) | Large GWAS |
| rs191137443 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs2092504 | TMEM51 | GWAS association (p=3.0e-08) | Large GWAS |
| rs7601792 | — | GWAS association (p=4.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.