Trait
SNPs associated with response to statin, LDL cholesterol change measurement
10 genetic variants across 5 genes have been associated with response to statin, LDL cholesterol change measurement in published research. Key genes include APOE, CELSR2, LPA.
Associated variants10 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs7528419 | CELSR2 | GWAS association (p=1.0e-17) | Large GWAS |
| rs58310495 | SLCO1B1 | GWAS association (p=7.0e-12) | Large GWAS |
| rs11591147 | PCSK9 | GWAS association (p=8.0e-10) | Large GWAS |
| rs150561664 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs5966882 | — | GWAS association (p=5.0e-09) | Large GWAS |
| rs2851341 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs67337506 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs1713222 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs7412 | APOE | GWAS association (p=1.0e-78) | Large GWAS |
| rs10455872 | LPA | GWAS association (p=1.0e-33) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.