Trait
SNPs associated with Serum Iron Amount
37 genetic variants across 15 genes have been associated with Serum Iron Amount in published research. Key genes include ABCA5, CD81, DUOX2.
Associated variants37 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs855791 | TMPRSS6 | GWAS association (p=1.0e-300) | Meta-analysis |
| rs1800562 | HFE | GWAS association (p=4.0e-276) | Meta-analysis |
| rs7385804 | TFR2 | GWAS association (p=9.0e-43) | Meta-analysis |
| rs9399136 | — | GWAS association (p=1.0e-36) | Meta-analysis |
| rs4854760 | — | GWAS association (p=6.0e-33) | Meta-analysis |
| rs35945185 | — | GWAS association (p=2.0e-13) | Meta-analysis |
| rs13007705 | ERFE | GWAS association (p=2.0e-12) | Meta-analysis |
| rs2005682 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs12718598 | IKZF1 | GWAS association (p=4.0e-11) | Meta-analysis |
| rs2228145 | IL6R | GWAS association (p=8.0e-11) | Meta-analysis |
| rs77262773 | ABCA5 | GWAS association (p=1.0e-09) | Meta-analysis |
| rs7630745 | — | GWAS association (p=2.0e-09) | Meta-analysis |
| rs57659670 | DUOX2 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs9376092 | LOC105378010 | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs11022542 | CD81 | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs13081052 | LRIG1 | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs62400295 | — | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs7775698 | — | GWAS association (p=7.0e-24) | Major Consortium Study |
| rs12328766 | — | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs8177252 | TF | GWAS association (p=3.0e-32) | Major Consortium Study |
| rs9402686 | LOC105378010 | GWAS association (p=6.0e-25) | Major Consortium Study |
| rs10831924 | CD81 | GWAS association (p=8.0e-15) | Major Consortium Study |
| rs28929474 | SERPINA1 | GWAS association (p=7.0e-21) | Major Consortium Study |
| rs738409 | PNPLA3 | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs8177248 | — | GWAS association (p=5.0e-23) | Major Consortium Study |
| rs13191659 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs144861591 | — | GWAS association (p=2.0e-47) | Major Consortium Study |
| rs3811647 | TF | GWAS association (p=1.0e-140) | Major Consortium Study |
| rs6762719 | TF | GWAS association (p=4.0e-215) | Major Consortium Study |
| rs1799945 | HFE | GWAS association (p=3.0e-09) | Large GWAS |
| rs4820268 | TMPRSS6 | GWAS association (p=4.0e-11) | Large GWAS |
| rs181143083 | ZDHHC14 | GWAS association (p=9.0e-10) | Large GWAS |
| rs115809796 | — | GWAS association (p=4.0e-09) | Large GWAS |
| rs202056061 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs111722075 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs113507773 | — | GWAS association (p=4.0e-08) | Large GWAS |
| rs2235321 | TMPRSS6 | GWAS association (p=3.0e-09) | Small GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.