Trait
SNPs associated with Toxic Nodular Goiter
32 genetic variants across 16 genes have been associated with Toxic Nodular Goiter in published research. Key genes include COMMD7, FGF7, INSR.
Associated variants32 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs73398264 | — | GWAS association (p=3.0e-108) | Major Consortium Study |
| rs17477923 | — | GWAS association (p=2.0e-81) | Major Consortium Study |
| rs12431502 | ITPK1 | GWAS association (p=2.0e-36) | Major Consortium Study |
| rs142698837 | TG | GWAS association (p=3.0e-31) | Major Consortium Study |
| rs3758723 | — | GWAS association (p=3.0e-30) | Major Consortium Study |
| rs4338740 | FGF7 | GWAS association (p=4.0e-29) | Major Consortium Study |
| rs10799824 | LOC105376817 | GWAS association (p=2.0e-28) | Major Consortium Study |
| rs1203925 | LNCNEF | GWAS association (p=5.0e-21) | Major Consortium Study |
| rs555310482 | LINC01603 | GWAS association (p=8.0e-21) | Major Consortium Study |
| rs73575085 | LOC105371356 | GWAS association (p=3.0e-20) | Major Consortium Study |
| rs675763 | LINC02869 | GWAS association (p=2.0e-18) | Major Consortium Study |
| rs925488 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs6085657 | — | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs8120176 | LOC105372687 | GWAS association (p=6.0e-14) | Major Consortium Study |
| rs6057634 | COMMD7 | GWAS association (p=3.0e-13) | Major Consortium Study |
| rs2853672 | TERT | GWAS association (p=4.0e-13) | Major Consortium Study |
| rs7907606 | — | GWAS association (p=5.0e-13) | Major Consortium Study |
| rs73234167 | NRG1 | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs30232 | — | GWAS association (p=2.0e-12) | Major Consortium Study |
| rs2980767 | — | GWAS association (p=3.0e-12) | Major Consortium Study |
| rs6990149 | LINC01603 | GWAS association (p=7.0e-12) | Major Consortium Study |
| rs4784295 | LOC102723323 | GWAS association (p=1.0e-11) | Major Consortium Study |
| rs66760320 | — | GWAS association (p=1.0e-31) | Major Consortium Study |
| rs10917469 | LOC105376817 | GWAS association (p=3.0e-47) | Major Consortium Study |
| rs116909374 | LOC124903302 | GWAS association (p=1.0e-31) | Major Consortium Study |
| rs1203930 | — | GWAS association (p=1.0e-86) | Major Consortium Study |
| rs12461206 | INSR | GWAS association (p=7.0e-41) | Major Consortium Study |
| rs334700 | NFIA | GWAS association (p=6.0e-44) | Major Consortium Study |
| rs4578973 | — | GWAS association (p=2.0e-24) | Major Consortium Study |
| rs7207781 | — | GWAS association (p=4.0e-16) | Major Consortium Study |
| rs73575086 | LOC105371356 | GWAS association (p=4.0e-37) | Major Consortium Study |
| rs9971770 | — | GWAS association (p=2.0e-27) | Major Consortium Study |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.