DPT

dermatopontin

Summary

Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. [provided by RefSeq, Jul 2008]

Known Variants26 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs6698023	1:168,665,792	C/T	—	benign
rs12060879	1:168,665,811	G/A	—	benign
rs748718975	1:168,665,849	G/A	missense variant	pathogenic
rs142020957	1:168,668,667	C/T	intron variant	—
rs752633076	1:168,670,336	T/C	—	uncertain significance
rs113856149	1:168,673,835	G/C	intron variant	—
rs78032017	1:168,683,471	G/A	missense variant	—
rs143058727	1:168,683,490	G/A	—	uncertain significance
rs570509194	1:168,683,500	A/G	—	likely benign
rs371792229	1:168,683,513	C/T	—	uncertain significance
rs143369045	1:168,683,529	C/T	—	benign
rs533619	1:168,685,805	C/A	—	—
rs573418	1:168,690,634	G/A	intron variant	—
rs531706	1:168,692,137	C/G	intron variant	—
rs190325124	1:168,695,374	G/C	intron variant	—
rs79594970	1:168,698,149	C/T	—	benign
rs150749597	1:168,698,165	C/A	—	likely benign
rs1466592586	1:168,698,172	G/T	—	uncertain significance
rs143980534	1:168,698,208	A/T	—	likely benign
rs146462912	1:168,698,238	C/T	—	uncertain significance
rs139513961	1:168,698,239	G/T	—	benign
rs749307060	1:168,698,285	C/T	—	uncertain significance
rs550327408	1:168,698,311	G/T	—	uncertain significance
rs1650316688	1:168,698,327	T/C	—	uncertain significance
rs77426373	1:168,698,405	A/G	—	benign
rs183286520	1:168,698,408	T/G	—	likely benign

Gene information from NCBI Gene. Variant classifications from ClinVar.