G2E3
G2/M-phase specific E3 ubiquitin protein ligase
Summary
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in apoptotic process and protein ubiquitination. Predicted to act upstream of or within blastocyst development; negative regulation of intrinsic apoptotic signaling pathway; and protein polyubiquitination. Located in Golgi apparatus and cytosol. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants28 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs229190 | 14:31,040,087 | T/A | — | — |
| rs229194 | 14:31,045,181 | G/C | — | — |
| rs229195 | 14:31,045,596 | G/C | — | — |
| rs370229233 | 14:31,055,939 | G/A | — | uncertain significance |
| rs561645245 | 14:31,055,996 | A/C | — | uncertain significance |
| rs2503010007 | 14:31,066,721 | T/G | — | uncertain significance |
| rs759202014 | 14:31,067,717 | G/A | — | uncertain significance |
| rs143107321 | 14:31,067,742 | A/G | — | uncertain significance |
| rs778321339 | 14:31,067,769 | G/A | — | uncertain significance |
| rs200128131 | 14:31,071,238 | C/T | — | uncertain significance |
| rs769526214 | 14:31,071,268 | G/T | — | uncertain significance |
| rs147737745 | 14:31,071,288 | C/A | — | uncertain significance |
| rs768652581 | 14:31,074,791 | T/G | — | uncertain significance |
| rs2503034550 | 14:31,074,802 | A/G | — | uncertain significance |
| rs760125501 | 14:31,074,809 | A/G | — | uncertain significance |
| rs2503035303 | 14:31,074,986 | C/G | — | uncertain significance |
| rs759532611 | 14:31,077,248 | C/G | — | uncertain significance |
| rs374380257 | 14:31,081,458 | G/C | — | uncertain significance |
| rs140574601 | 14:31,081,545 | G/C | — | uncertain significance |
| rs229243 | 14:31,083,748 | C/G | — | — |
| rs745437632 | 14:31,084,614 | C/T | — | uncertain significance |
| rs746775640 | 14:31,084,644 | A/C | — | uncertain significance |
| rs748044271 | 14:31,084,658 | A/G | — | uncertain significance |
| rs777529895 | 14:31,085,594 | G/A | — | uncertain significance |
| rs763569314 | 14:31,085,684 | A/G | — | uncertain significance |
| rs1340650006 | 14:31,085,685 | T/G | — | uncertain significance |
| rs773998300 | 14:31,085,696 | C/G | — | uncertain significance |
| rs755794844 | 14:31,085,729 | A/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.