Trait
SNPs associated with Frontotemporal Dementia
12 genetic variants across 8 genes have been associated with Frontotemporal Dementia in published research. Key genes include APOE, ERGIC1, G2E3.
Associated variants12 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs553913507 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs903914982 | SYNE1 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs429358 | APOE | GWAS association (p=8.0e-37) | Major Consortium Study |
| rs12554036 | — | GWAS association (p=8.0e-40) | Large GWAS |
| rs12608932 | UNC13A | GWAS association (p=7.0e-26) | Large GWAS |
| rs229243 | G2E3 | GWAS association (p=5.0e-11) | Large GWAS |
| rs4676496 | — | GWAS association (p=9.0e-10) | Large GWAS |
| rs4810992 | RNF114 | GWAS association (p=4.0e-09) | Large GWAS |
| rs9268856 | — | GWAS association (p=6.0e-09) | Large GWAS |
| rs517339 | ERGIC1 | GWAS association (p=1.0e-08) | Large GWAS |
| rs36196656 | GFRA2 | GWAS association (p=2.0e-08) | Large GWAS |
| rs7791726 | TMEM106B | GWAS association (p=4.0e-16) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.