Trait

SNPs associated with Amyotrophic Lateral Sclerosis

27 genetic variants across 16 genes have been associated with Amyotrophic Lateral Sclerosis in published research. Key genes include ACSL5, C9orf72, CFAP410.

Associated variants27 total

rsidGeneEffectEvidence
rs12608932UNC13AGWAS association (p=5.0e-08)Meta-analysis
rs3736947ACSL5GWAS association (p=8.0e-11)Meta-analysis
rs3849943—GWAS association (p=6.0e-10)Meta-analysis
rs80265967SOD1GWAS association (p=4.0e-18)Large GWAS
rs7019351—GWAS association (p=3.0e-15)Large GWAS
rs229195G2E3GWAS association (p=9.0e-15)Large GWAS
rs229194G2E3GWAS association (p=9.0e-15)Large GWAS
rs631312—GWAS association (p=3.0e-12)Large GWAS
rs9275477—GWAS association (p=4.0e-12)Large GWAS
rs113247976KIF5AGWAS association (p=1.0e-11)Large GWAS
rs75087725CFAP410GWAS association (p=3.0e-11)Large GWAS
rs10463311—GWAS association (p=3.0e-10)Large GWAS
rs17785991SLC9A8GWAS association (p=3.0e-10)Large GWAS
rs58854276—GWAS association (p=7.0e-10)Large GWAS
rs8141797SUSD2GWAS association (p=2.0e-09)Large GWAS
rs4075094TBK1GWAS association (p=2.0e-09)Large GWAS
rs517339ERGIC1GWAS association (p=6.0e-09)Large GWAS
rs62333164—GWAS association (p=7.0e-09)Large GWAS
rs2985994—GWAS association (p=1.0e-08)Large GWAS
rs1541160KIFAP3GWAS association (p=2.0e-08)Large GWAS
rs10280711PTPRN2GWAS association (p=2.0e-08)Large GWAS
rs6703183LOC105372898GWAS association (p=3.0e-08)Large GWAS
rs855913—GWAS association (p=4.0e-08)Large GWAS
rs10260404DPP6GWAS association (p=5.0e-08)Large GWAS
rs2453555C9orf72GWAS association (p=1.0e-43)Large GWAS
rs3849942—GWAS association (p=9.0e-11)Small GWAS
rs13048019TIAM1GWAS association (p=3.0e-08)Small GWAS

Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.

Amyotrophic Lateral Sclerosis — SNPs & genetic associations — Gene Wizard