LRP4

LDL receptor related protein 4

Summary

This gene encodes a member of the low-density lipoprotein receptor-related protein family. The encoded protein may be a regulator of Wnt signaling. Mutations in this gene are associated with Cenani-Lenz syndrome. [provided by RefSeq, May 2010]

Known Variants1,067 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs188545674	11:46,878,282	C/T	—	benign
rs886048339	11:46,878,322	G/A	—	uncertain significance
rs7928628	11:46,878,430	G/C	—	likely benign
rs76159791	11:46,878,454	A/G	—	benign
rs151112380	11:46,878,480	G/A	—	likely benign
rs558730059	11:46,878,807	C/T	—	uncertain significance
rs886048341	11:46,878,872	G/T	—	uncertain significance
rs544836196	11:46,878,907	T/C	—	benign
rs774819807	11:46,878,948	A/C	—	uncertain significance
rs1420065241	11:46,878,988	G/A	—	uncertain significance
rs1940410910	11:46,879,067	G/A	—	uncertain significance
rs75558883	11:46,879,089	T/C	—	benign
rs550964500	11:46,879,199	C/T	—	uncertain significance
rs567606707	11:46,879,212	C/A	—	uncertain significance
rs1259687722	11:46,879,261	C/G	—	uncertain significance
rs116705878	11:46,879,383	G/A	—	benign
rs886048343	11:46,879,470	G/C	—	uncertain significance
rs10838623	11:46,879,517	G/A	—	benign
rs79910473	11:46,879,605	G/T	—	likely benign
rs771309941	11:46,879,613	T/G	—	uncertain significance
rs886048344	11:46,879,754	G/A	—	uncertain significance
rs886048345	11:46,879,800	G/C	—	uncertain significance
rs1940431939	11:46,879,869	C/G	—	uncertain significance
rs547315814	11:46,879,925	T/A	—	uncertain significance
rs3829940	11:46,879,973	A/G	—	benign
rs1940440653	11:46,880,119	G/C	—	uncertain significance
rs561326679	11:46,880,155	G/A	—	uncertain significance
rs532378480	11:46,880,162	C/T	—	uncertain significance
rs1940441759	11:46,880,171	G/A	—	uncertain significance
rs1422186695	11:46,880,205	A/G	—	uncertain significance
rs886048347	11:46,880,229	G/A	—	uncertain significance
rs77376145	11:46,880,273	G/T	—	likely benign
rs890348934	11:46,880,292	C/T	—	uncertain significance
rs536278440	11:46,880,430	G/A	—	uncertain significance
rs147627264	11:46,880,480	C/T	—	likely benign
rs372674165	11:46,880,490	A/G	—	uncertain significance
rs2134750322	11:46,880,537	G/C	—	likely benign
rs1940457917	11:46,880,554	A/G	—	uncertain significance
rs751359851	11:46,880,579	C/T	—	likely benign
rs372637156	11:46,880,580	G/A	—	uncertain significance
rs749482785	11:46,880,583	T/C	—	uncertain significance
rs149082597	11:46,880,592	G/C	—	conflicting classifications of pathogenicity
rs779079160	11:46,880,598	C/T	—	uncertain significance
rs147138337	11:46,880,599	G/A	—	uncertain significance
rs377204138	11:46,880,602	T/C	—	uncertain significance
rs1940461595	11:46,880,619	G/A	—	uncertain significance
rs761403316	11:46,880,626	C/T	—	uncertain significance
rs764879036	11:46,880,627	G/A	—	likely benign
rs1312872252	11:46,880,634	C/T	—	uncertain significance
rs1940462523	11:46,880,639	A/G	—	likely benign
rs772708591	11:46,880,642	C/T	—	likely benign
rs2539689187	11:46,880,644	G/A	—	uncertain significance
rs762431184	11:46,880,645	C/G	—	uncertain significance
rs751494811	11:46,880,666	C/T	—	likely benign
rs368840169	11:46,880,667	G/A	—	uncertain significance
rs2539689273	11:46,880,675	G/C	—	uncertain significance
rs767372541	11:46,880,678	A/G	—	likely benign
rs139535571	11:46,880,694	C/T	—	uncertain significance
rs200514161	11:46,880,696	G/A	—	likely benign
rs2539689353	11:46,880,702	G/A	—	likely benign
rs780576799	11:46,880,711	C/A	—	likely benign
rs375391856	11:46,880,712	G/A	—	uncertain significance
rs769171471	11:46,880,714	G/A	—	likely benign
rs149687723	11:46,880,720	C/T	—	likely benign
rs769426991	11:46,880,728	A/G	—	uncertain significance
rs144350829	11:46,880,732	A/G	—	conflicting classifications of pathogenicity
rs770309253	11:46,880,739	C/T	—	uncertain significance
rs199969059	11:46,880,740	G/A	—	uncertain significance
rs759491078	11:46,880,742	A/G	—	uncertain significance
rs767566588	11:46,880,744	G/A	—	likely benign
rs1031449863	11:46,880,745	A/G	—	uncertain significance
rs2134750890	11:46,880,746	G/C	—	uncertain significance
rs560166088	11:46,880,747	G/C	—	likely benign
rs142462686	11:46,880,752	C/G	—	uncertain significance
rs2134750971	11:46,880,753	C/G	—	likely benign
rs771256759	11:46,880,754	C/A	—	uncertain significance
rs911721294	11:46,880,759	G/A	—	likely benign
rs146864522	11:46,880,763	C/T	—	uncertain significance
rs1940472316	11:46,880,787	T/C	—	uncertain significance
rs886043837	11:46,880,796	T/A	—	uncertain significance
rs760515633	11:46,880,811	C/G	—	uncertain significance
rs991397044	11:46,880,814	A/G	—	uncertain significance
rs779299308	11:46,880,824	C/T	—	uncertain significance
rs373162825	11:46,880,826	A/T	—	uncertain significance
rs772706817	11:46,880,828	C/T	—	likely benign
rs1470893503	11:46,880,843	G/A	—	likely benign
rs140715783	11:46,880,850	T/C	—	uncertain significance
rs756670241	11:46,880,862	C/T	—	uncertain significance
rs373551673	11:46,880,870	G/C	—	likely benign
rs2539689955	11:46,880,878	A/G	—	uncertain significance
rs370288647	11:46,884,144	T/C	—	likely benign
rs778676466	11:46,884,164	T/G	—	uncertain significance
rs758146599	11:46,884,167	T/C	—	uncertain significance
rs146542222	11:46,884,168	A/G	—	uncertain significance
rs376540994	11:46,884,172	C/T	—	likely benign
rs1208850907	11:46,884,180	T/G	—	uncertain significance
rs61748876	11:46,884,185	A/G	—	uncertain significance
rs759701000	11:46,884,196	G/C	—	conflicting classifications of pathogenicity
rs541585714	11:46,884,212	T/G	—	conflicting classifications of pathogenicity
rs765647853	11:46,884,223	T/C	—	likely benign

Showing 100 of 1,067 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.