MAOA

monoamine oxidase A

Summary

This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]

Known Variants168 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs5953210	X:43,514,046	G/A	regulatory region variant	—
rs2519102839	X:43,515,024	C/T	—	uncertain significance
rs1601921232	X:43,515,592	G/A	—	uncertain significance
rs2147066663	X:43,515,604	G/A	—	likely benign
rs2519103578	X:43,515,609	C/T	—	uncertain significance
rs1347324620	X:43,515,619	G/A	—	likely benign
rs2519103647	X:43,515,645	T/C	—	uncertain significance
rs2519103684	X:43,515,681	G/C	—	likely benign
rs3788862	X:43,517,364	A/C	—	—
rs5906883	X:43,526,943	A/C	intron variant	—
rs1465107	X:43,538,017	A/G	intron variant	—
rs887473112	X:43,542,752	T/A	—	likely benign
rs1196492976	X:43,542,755	C/T	—	likely benign
rs1131691720	X:43,542,782	T/C	—	uncertain significance
rs779299641	X:43,542,796	G/A	—	uncertain significance
rs796065312	X:43,542,820	C/T	missense variant	pathogenic
rs201519600	X:43,542,824	A/G	—	uncertain significance
rs2147080866	X:43,542,835	G/A	—	uncertain significance
rs747281025	X:43,542,850	A/G	—	uncertain significance
rs2033460886	X:43,542,858	A/G	—	uncertain significance
rs2033460975	X:43,542,861	T/C	—	likely benign
rs5906957	X:43,547,310	A/T	—	—
rs759325782	X:43,552,541	G/A	—	uncertain significance
rs180855715	X:43,552,555	C/T	—	likely benign
rs2033551075	X:43,552,556	G/A	—	uncertain significance
rs754172029	X:43,552,557	T/C	—	uncertain significance
rs750916164	X:43,552,604	C/G	—	uncertain significance
rs1290392482	X:43,552,605	G/A	—	uncertain significance
rs1601935224	X:43,552,624	C/G	—	likely benign
rs780148935	X:43,552,625	A/G	—	uncertain significance
rs747229681	X:43,552,629	A/G	—	uncertain significance
rs2033551853	X:43,552,649	A/G	—	uncertain significance
rs910533865	X:43,552,651	T/C	—	likely benign
rs2147085459	X:43,552,659	T/C	—	uncertain significance
rs148788403	X:43,552,691	C/A	—	benign
rs759124186	X:43,552,693	C/A	—	likely benign
rs2283725	X:43,559,976	A/T	—	—
rs754942975	X:43,571,100	G/C	—	likely benign
rs375206098	X:43,571,101	T/C	—	likely benign
rs140295792	X:43,571,137	C/T	—	uncertain significance
rs748344922	X:43,571,142	C/T	—	likely benign
rs755919316	X:43,571,143	G/A	—	uncertain significance
rs1252486956	X:43,571,167	A/G	—	uncertain significance
rs201799429	X:43,571,186	A/G	—	uncertain significance
rs1800464	X:43,571,197	A/T	—	uncertain significance
rs1555947954	X:43,571,212	A/G	—	uncertain significance
rs771740634	X:43,571,214	G/A	—	uncertain significance
rs2519144828	X:43,571,217	G/A	—	likely benign
rs2519144831	X:43,571,223	G/A	—	uncertain significance
rs2033703535	X:43,571,235	G/A	—	uncertain significance
rs767547104	X:43,571,932	G/A	—	likely benign
rs763906089	X:43,571,939	C/T	—	likely benign
rs369122751	X:43,571,946	C/G	—	likely benign
rs373044189	X:43,571,961	G/A	—	uncertain significance
rs1555948045	X:43,571,964	G/T	—	uncertain significance
rs2519145492	X:43,571,988	G/A	—	uncertain significance
rs2519145529	X:43,572,016	A/G	—	uncertain significance
rs574432879	X:43,572,022	T/C	—	conflicting classifications of pathogenicity
rs58524323	X:43,587,431	G/A	—	benign
rs2519157567	X:43,587,458	A/G	—	uncertain significance
rs2147101580	X:43,587,471	G/C	—	uncertain significance
rs142659522	X:43,587,481	G/T	—	conflicting classifications of pathogenicity
rs2033854601	X:43,587,492	G/T	—	likely benign
rs778901381	X:43,587,519	C/T	—	likely benign
rs780043965	X:43,587,551	A/G	—	conflicting classifications of pathogenicity
rs1298680902	X:43,587,574	T/A	—	uncertain significance
rs2519160033	X:43,590,489	A/G	—	uncertain significance
rs765118799	X:43,590,492	G/A	—	uncertain significance
rs758225239	X:43,590,523	C/T	—	likely benign
rs370853887	X:43,590,544	C/T	—	likely benign
rs368201051	X:43,590,545	G/A	—	uncertain significance
rs2033878817	X:43,590,552	A/T	—	uncertain significance
rs1135401773	X:43,590,572	G/A	—	likely pathogenic
rs980804164	X:43,590,574	C/T	—	likely benign
rs2519160155	X:43,590,578	C/A	—	uncertain significance
rs1326709993	X:43,590,580	C/G	—	uncertain significance
rs777420059	X:43,590,581	G/A	—	conflicting classifications of pathogenicity
rs796065311	X:43,590,591	—	—	pathogenic
rs2147102887	X:43,590,608	A/G	—	uncertain significance
rs373791136	X:43,590,616	G/A	—	likely benign
rs1555950128	X:43,590,638	G/A	—	uncertain significance
rs1321478580	X:43,590,926	T/G	—	likely benign
rs755014579	X:43,590,931	T/C	—	uncertain significance
rs2033882536	X:43,590,932	G/A	—	likely benign
rs587777457	X:43,590,942	G/T	missense variant	pathogenic
rs752147192	X:43,590,949	C/T	—	likely benign
rs150176511	X:43,590,950	G/A	—	uncertain significance
rs2147103024	X:43,590,957	A/G	—	conflicting classifications of pathogenicity
rs751223564	X:43,590,961	G/A	—	benign
rs138703731	X:43,590,970	G/A	—	conflicting classifications of pathogenicity
rs2519160707	X:43,590,976	G/A	—	likely benign
rs72554632	X:43,591,031	C/T	stop gained	pathogenic
rs780647851	X:43,591,035	G/A	—	uncertain significance
rs6323	X:43,591,036	G/T	synonymous variant	benign
rs144688481	X:43,591,078	G/T	—	conflicting classifications of pathogenicity
rs763280736	X:43,591,104	G/A	—	uncertain significance
rs780408416	X:43,591,938	T/G	—	likely benign
rs769967831	X:43,591,953	T/C	—	likely benign
rs2033892290	X:43,591,993	A/G	—	uncertain significance
rs2519161693	X:43,592,029	C/T	—	uncertain significance

Showing 100 of 168 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.