MARK3

microtubule affinity regulating kinase 3

Summary

The protein encoded by this gene is activated by phosphorylation and in turn is involved in the phosphorylation of tau proteins MAP2 and MAP4. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Known Variants66 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs3759575	14:103,850,424	A/T	—	—
rs3759576	14:103,850,433	C/T	—	—
rs11627567	14:103,851,775	C/T	regulatory region variant	—
rs376529319	14:103,852,409	A/G	—	uncertain significance
rs12889639	14:103,860,206	G/C	—	—
rs12890750	14:103,860,309	T/G	regulatory region variant	—
rs56227024	14:103,861,706	A/G	—	—
rs78938152	14:103,865,361	A/G	regulatory region variant	—
rs569205142	14:103,871,474	G/A	—	uncertain significance
rs551785219	14:103,871,486	C/T	—	uncertain significance
rs767880418	14:103,871,507	A/C	—	uncertain significance
rs750895691	14:103,871,511	A/G	—	likely benign
rs1443294757	14:103,871,512	C/T	—	uncertain significance
rs12889703	14:103,872,951	T/C	—	—
rs4900574	14:103,879,024	G/C	coding sequence variant	—
rs11623869	14:103,883,633	G/A	—	—
rs35233301	14:103,885,291	A/T	—	—
rs17679127	14:103,890,091	A/G	regulatory region variant	—
rs62007683	14:103,894,071	G/T	regulatory region variant	—
rs62007684	14:103,894,223	T/C	regulatory region variant	—
rs1179115060	14:103,894,776	A/G	—	uncertain significance
rs17679259	14:103,895,302	A/G	intron variant	—
rs4900575	14:103,899,169	G/C	intron variant	—
rs35339837	14:103,910,983	G/T	—	—
rs17095251	14:103,913,782	G/A	intron variant	—
rs572627741	14:103,918,324	A/T	—	likely benign
rs143574994	14:103,920,257	C/G	intron variant	—
rs10141120	14:103,923,008	T/C	regulatory region variant	—
rs2273699	14:103,923,475	A/G	—	benign
rs2505977351	14:103,932,316	G/A	—	uncertain significance
rs200117383	14:103,932,417	G/A	—	uncertain significance
rs1211526313	14:103,932,696	G/A	—	uncertain significance
rs560167611	14:103,932,750	A/G	—	uncertain significance
rs376654076	14:103,933,421	A/G	—	uncertain significance
rs749743518	14:103,934,376	G/T	—	uncertain significance
rs747903624	14:103,934,401	A/G	—	uncertain significance
rs201880493	14:103,934,427	A/C	—	uncertain significance
rs142938235	14:103,941,358	G/A	—	benign
rs369682757	14:103,941,362	C/G	—	uncertain significance
rs201851374	14:103,941,363	C/T	—	uncertain significance
rs56134485	14:103,941,379	C/A	—	benign
rs56305318	14:103,941,392	A/G	—	benign
rs2506145955	14:103,941,450	G/A	—	uncertain significance
rs56126530	14:103,941,454	A/G	—	benign
rs1205269209	14:103,946,831	G/C	—	likely benign
rs12878548	14:103,953,501	G/C	—	—
rs866468469	14:103,958,163	A/G	—	uncertain significance
rs369866994	14:103,958,188	G/A	—	uncertain significance
rs1207865053	14:103,958,226	G/C	—	uncertain significance
rs376395495	14:103,958,235	C/G	—	pathogenic
rs775520582	14:103,958,242	G/A	—	uncertain significance
rs56365443	14:103,960,026	A/G	intron variant	—
rs372826694	14:103,966,496	T/C	—	likely benign
rs902962601	14:103,966,517	C/T	—	likely benign
rs773581917	14:103,966,522	G/C	—	uncertain significance
rs557344866	14:103,969,208	A/G	—	uncertain significance
rs773826573	14:103,969,224	A/G	—	uncertain significance
rs759344240	14:103,969,331	C/T	—	uncertain significance
rs752638401	14:103,969,337	A/G	—	uncertain significance
rs371959467	14:103,969,339	C/G	—	uncertain significance
rs771652517	14:103,969,367	G/T	—	uncertain significance
rs200539165	14:103,969,399	C/G	—	uncertain significance
rs763946087	14:103,969,501	A/G	—	uncertain significance
rs201508144	14:103,969,503	C/T	—	likely benign
rs760693719	14:103,969,508	A/G	—	uncertain significance
rs2507350655	14:103,969,518	C/T	—	uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.