MTHFD2L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like
Summary
Predicted to enable methenyltetrahydrofolate cyclohydrolase activity; methylenetetrahydrofolate dehydrogenase (NAD+) activity; and methylenetetrahydrofolate dehydrogenase (NADP+) activity. Predicted to be involved in tetrahydrofolate interconversion. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants39 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs189986015 | 4:74,986,047 | G/T | intron variant | — |
| rs114868521 | 4:74,988,491 | C/T | upstream gene variant | — |
| rs11737357 | 4:74,996,395 | A/G | intron variant | — |
| rs190689643 | 4:74,997,153 | C/G | intron variant | — |
| rs139220692 | 4:75,006,661 | C/T | intron variant | — |
| rs1006120574 | 4:75,023,967 | G/C | — | uncertain significance |
| rs766671502 | 4:75,023,971 | T/A | — | uncertain significance |
| rs543715253 | 4:75,023,976 | G/A | — | uncertain significance |
| rs2475732606 | 4:75,023,977 | G/C | — | uncertain significance |
| rs1300774482 | 4:75,040,242 | T/C | — | uncertain significance |
| rs1273138399 | 4:75,040,246 | G/T | — | uncertain significance |
| rs61744957 | 4:75,040,404 | G/A | — | uncertain significance |
| rs774406514 | 4:75,041,015 | A/G | — | uncertain significance |
| rs768645728 | 4:75,041,073 | A/T | — | uncertain significance |
| rs2109961647 | 4:75,041,087 | G/A | — | uncertain significance |
| rs1263999247 | 4:75,041,096 | A/T | — | uncertain significance |
| rs114961484 | 4:75,045,493 | C/A | intron variant | — |
| rs1481754207 | 4:75,065,537 | A/C | — | uncertain significance |
| rs144442266 | 4:75,065,541 | G/A | — | not provided |
| rs572530786 | 4:75,065,583 | A/G | — | uncertain significance |
| rs1273027213 | 4:75,065,609 | C/T | — | uncertain significance |
| rs1039052766 | 4:75,065,653 | A/G | — | uncertain significance |
| rs370317706 | 4:75,066,980 | G/T | — | uncertain significance |
| rs763669844 | 4:75,066,985 | C/G | — | likely benign |
| rs148832175 | 4:75,067,004 | T/G | — | uncertain significance |
| rs1157206024 | 4:75,067,006 | G/A | — | uncertain significance |
| rs2476087275 | 4:75,067,037 | T/C | — | uncertain significance |
| rs1219541178 | 4:75,067,051 | C/G | — | uncertain significance |
| rs199612978 | 4:75,067,064 | A/C | — | uncertain significance |
| rs74994406 | 4:75,069,911 | C/T | intron variant | — |
| rs182616603 | 4:75,084,732 | C/T | intron variant | — |
| rs9995671 | 4:75,085,218 | G/A | regulatory region variant | — |
| rs372906934 | 4:75,091,057 | A/G | — | uncertain significance |
| rs7676269 | 4:75,093,640 | A/T | intron variant | — |
| rs7683181 | 4:75,103,676 | C/G | — | — |
| rs77287883 | 4:75,107,171 | C/T | intron variant | — |
| rs77737974 | 4:75,121,068 | A/G | intron variant | — |
| rs75868097 | 4:75,148,954 | T/A | regulatory region variant | — |
| rs16850864 | 4:75,160,824 | C/T | intron variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.