NDRG2
NDRG family member 2
Summary
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Known Variants24 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs142730462 | 14:21,485,784 | G/A | — | uncertain significance |
| rs768301542 | 14:21,485,795 | G/A | — | uncertain significance |
| rs755833924 | 14:21,486,193 | C/T | — | uncertain significance |
| rs35076247 | 14:21,486,671 | A/G | — | benign |
| rs200458592 | 14:21,487,276 | T/C | — | uncertain significance |
| rs748565093 | 14:21,487,317 | C/A | — | uncertain significance |
| rs1297280565 | 14:21,487,846 | T/C | — | uncertain significance |
| rs1466516055 | 14:21,487,859 | T/G | — | uncertain significance |
| rs374852149 | 14:21,487,873 | A/G | — | uncertain significance |
| rs2043200876 | 14:21,488,659 | T/C | — | uncertain significance |
| rs558685962 | 14:21,488,957 | G/C | — | uncertain significance |
| rs375087853 | 14:21,488,996 | T/C | — | uncertain significance |
| rs142791780 | 14:21,489,992 | C/T | — | likely benign |
| rs149741442 | 14:21,490,003 | A/G | — | uncertain significance |
| rs1309462990 | 14:21,490,261 | C/A | — | uncertain significance |
| rs138902025 | 14:21,490,582 | C/A | — | benign |
| rs1444235304 | 14:21,490,592 | T/G | — | uncertain significance |
| rs36007455 | 14:21,490,641 | T/A | — | benign |
| rs1386852940 | 14:21,491,425 | G/A | — | uncertain significance |
| rs1998848 | 14:21,492,229 | G/A | regulatory region variant | — |
| rs147773754 | 14:21,492,374 | C/T | coding sequence variant | — |
| rs539018113 | 14:21,493,765 | G/T | — | — |
| rs3748348 | 14:21,501,195 | G/A | synonymous variant | — |
| rs143881017 | 14:21,502,029 | C/T | missense variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.