RANBP17
RAN binding protein 17
Summary
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]
Known Variants126 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs7722812 | 5:170,287,636 | A/T | — | — |
| rs7722978 | 5:170,287,698 | A/C | — | — |
| rs11749349 | 5:170,288,922 | A/C | — | — |
| rs550500951 | 5:170,289,029 | C/A | — | likely benign |
| rs1019528897 | 5:170,289,036 | A/G | — | likely benign |
| rs1030666282 | 5:170,289,047 | C/T | — | uncertain significance |
| rs139675546 | 5:170,289,050 | T/C | — | benign |
| rs149220188 | 5:170,305,142 | A/G | — | uncertain significance |
| rs200328963 | 5:170,305,162 | G/C | — | uncertain significance |
| rs781090413 | 5:170,305,243 | G/A | — | uncertain significance |
| rs2532579426 | 5:170,308,895 | A/G | — | uncertain significance |
| rs141535602 | 5:170,319,406 | A/G | — | likely benign |
| rs763981721 | 5:170,319,424 | C/T | — | uncertain significance |
| rs867165048 | 5:170,319,435 | C/A | — | uncertain significance |
| rs1345275239 | 5:170,319,556 | A/G | — | uncertain significance |
| rs200553254 | 5:170,323,055 | G/A | — | uncertain significance |
| rs2339171 | 5:170,323,682 | C/G | — | — |
| rs6880972 | 5:170,323,843 | T/C | regulatory region variant | — |
| rs4380681 | 5:170,328,944 | G/A | intron variant | — |
| rs139178386 | 5:170,336,681 | C/G | — | likely benign |
| rs80184931 | 5:170,336,704 | G/A | — | benign |
| rs148659070 | 5:170,336,722 | A/T | — | benign |
| rs1771377522 | 5:170,336,734 | G/A | — | uncertain significance |
| rs2532317048 | 5:170,336,755 | T/G | — | uncertain significance |
| rs199794174 | 5:170,336,764 | A/G | — | uncertain significance |
| rs764555881 | 5:170,338,004 | A/G | — | uncertain significance |
| rs139981430 | 5:170,338,070 | T/C | — | likely benign |
| rs373879236 | 5:170,338,109 | C/T | — | uncertain significance |
| rs140960205 | 5:170,343,530 | G/T | — | uncertain significance |
| rs2532367039 | 5:170,343,553 | A/G | — | uncertain significance |
| rs150264798 | 5:170,343,584 | C/G | — | uncertain significance |
| rs1179241271 | 5:170,345,717 | G/A | — | uncertain significance |
| rs973323772 | 5:170,345,739 | A/G | — | uncertain significance |
| rs2532384129 | 5:170,345,762 | G/C | — | uncertain significance |
| rs371757436 | 5:170,345,777 | A/G | — | uncertain significance |
| rs780638378 | 5:170,345,778 | A/G | — | uncertain significance |
| rs1772191088 | 5:170,345,814 | A/G | — | uncertain significance |
| rs145822469 | 5:170,345,819 | G/C | — | likely benign |
| rs1028326934 | 5:170,346,503 | T/C | — | uncertain significance |
| rs200032818 | 5:170,346,589 | C/T | — | uncertain significance |
| rs369037414 | 5:170,346,590 | G/T | — | uncertain significance |
| rs766365499 | 5:170,346,613 | G/A | — | uncertain significance |
| rs141644933 | 5:170,351,370 | A/T | — | uncertain significance |
| rs1480014947 | 5:170,351,419 | T/G | — | uncertain significance |
| rs369051193 | 5:170,351,426 | C/T | — | uncertain significance |
| rs2532427525 | 5:170,351,464 | C/T | — | uncertain significance |
| rs936289583 | 5:170,351,548 | C/G | — | uncertain significance |
| rs9313530 | 5:170,368,907 | A/G | — | — |
| rs973605 | 5:170,372,817 | G/T | intron variant | — |
| rs756479184 | 5:170,380,654 | A/G | — | uncertain significance |
| rs970969183 | 5:170,380,676 | A/G | — | uncertain significance |
| rs2532635141 | 5:170,380,699 | T/C | — | uncertain significance |
| rs112551059 | 5:170,384,113 | G/A | — | — |
| rs3849710 | 5:170,389,532 | G/A | intron variant | — |
| rs13166557 | 5:170,392,903 | T/G | intron variant | — |
| rs1776732226 | 5:170,395,260 | T/C | — | uncertain significance |
| rs2532766444 | 5:170,395,335 | A/G | — | uncertain significance |
| rs969557166 | 5:170,395,340 | C/T | — | uncertain significance |
| rs10070758 | 5:170,439,072 | G/A | — | — |
| rs144100666 | 5:170,447,077 | G/A | intron variant | — |
| rs10475973 | 5:170,449,000 | A/G | intron variant | — |
| rs4286697 | 5:170,454,681 | A/G | intron variant | — |
| rs2441019 | 5:170,468,415 | T/C | — | — |
| rs2127639991 | 5:170,471,310 | A/G | — | uncertain significance |
| rs2591485 | 5:170,482,901 | C/T | — | — |
| rs810496 | 5:170,484,975 | A/G | intron variant | — |
| rs245753 | 5:170,486,143 | T/C | — | — |
| rs779655 | 5:170,495,158 | G/C | intron variant | — |
| rs779661 | 5:170,499,601 | T/A | — | — |
| rs10073714 | 5:170,516,283 | C/T | — | — |
| rs2608101 | 5:170,516,570 | T/G | — | — |
| rs245767 | 5:170,525,393 | A/C | — | — |
| rs245768 | 5:170,526,094 | A/G | — | — |
| rs245769 | 5:170,529,335 | C/G | — | — |
| rs245775 | 5:170,532,105 | A/T | — | — |
| rs29648 | 5:170,559,580 | A/T | — | — |
| rs36104512 | 5:170,597,190 | G/A | — | benign |
| rs747480763 | 5:170,598,215 | C/G | — | uncertain significance |
| rs2534223977 | 5:170,610,178 | C/T | — | uncertain significance |
| rs201196825 | 5:170,610,215 | T/G | — | uncertain significance |
| rs774753172 | 5:170,610,349 | C/T | — | likely benign |
| rs1027940208 | 5:170,610,405 | C/T | — | uncertain significance |
| rs2339234 | 5:170,612,546 | G/T | — | — |
| rs374054397 | 5:170,626,676 | G/A | — | uncertain significance |
| rs367978664 | 5:170,626,679 | G/A | — | uncertain significance |
| rs1458313890 | 5:170,626,681 | T/A | — | uncertain significance |
| rs748423749 | 5:170,626,698 | A/C | — | uncertain significance |
| rs35724654 | 5:170,626,735 | A/G | — | benign |
| rs1376180114 | 5:170,632,546 | G/A | — | uncertain significance |
| rs2534342390 | 5:170,632,553 | A/C | — | uncertain significance |
| rs2534342489 | 5:170,632,561 | G/C | — | uncertain significance |
| rs753684946 | 5:170,632,597 | A/G | — | uncertain significance |
| rs201127616 | 5:170,640,643 | C/T | — | uncertain significance |
| rs149025321 | 5:170,640,676 | G/A | — | likely benign |
| rs764203470 | 5:170,640,678 | T/G | — | uncertain significance |
| rs34536688 | 5:170,640,694 | C/T | — | benign |
| rs1248091926 | 5:170,640,732 | A/G | — | uncertain significance |
| rs201284839 | 5:170,648,770 | G/A | — | uncertain significance |
| rs138187228 | 5:170,667,254 | A/G | intron variant | — |
| rs747989648 | 5:170,668,051 | T/C | — | uncertain significance |
Showing 100 of 126 variants. Use the SNP search for the full list.
Gene information from NCBI Gene. Variant classifications from ClinVar.