SLC41A1
solute carrier family 41 member 1
Summary
Enables magnesium:sodium antiporter activity. Involved in cellular response to magnesium ion; intracellular magnesium ion homeostasis; and magnesium ion transmembrane transport. Located in basolateral plasma membrane. Part of protein-containing complex. Implicated in nephronophthisis. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants80 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1775148 | 1:205,757,824 | C/A | — | — |
| rs151188261 | 1:205,759,636 | C/T | 3 prime UTR variant | — |
| rs753516125 | 1:205,760,677 | G/A | — | uncertain significance |
| rs778685596 | 1:205,760,683 | C/T | — | uncertain significance |
| rs768929818 | 1:205,760,738 | G/C | — | uncertain significance |
| rs2526619372 | 1:205,760,760 | G/A | — | likely benign |
| rs35576575 | 1:205,760,832 | C/T | — | benign |
| rs2526619575 | 1:205,760,833 | A/C | — | uncertain significance |
| rs371831150 | 1:205,760,837 | G/C | — | uncertain significance |
| rs1365622627 | 1:205,760,840 | T/C | — | uncertain significance |
| rs769019951 | 1:205,760,850 | G/C | — | likely benign |
| rs823154 | 1:205,762,406 | C/T | regulatory region variant | — |
| rs781224024 | 1:205,764,014 | G/A | — | uncertain significance |
| rs200540955 | 1:205,764,025 | G/T | — | likely benign |
| rs151305052 | 1:205,764,031 | G/A | — | benign |
| rs369862450 | 1:205,764,108 | C/T | — | uncertain significance |
| rs913088171 | 1:205,764,122 | A/G | — | uncertain significance |
| rs181756408 | 1:205,764,198 | C/T | intron variant | — |
| rs56052552 | 1:205,764,433 | A/C | — | benign |
| rs141622561 | 1:205,764,457 | G/A | — | benign |
| rs200085602 | 1:205,764,467 | G/A | — | uncertain significance |
| rs764080771 | 1:205,764,484 | A/T | — | uncertain significance |
| rs368438972 | 1:205,764,507 | C/T | — | uncertain significance |
| rs781347037 | 1:205,764,511 | G/A | — | uncertain significance |
| rs145225878 | 1:205,764,518 | T/C | — | likely benign |
| rs372104416 | 1:205,764,622 | C/T | — | likely benign |
| rs376824280 | 1:205,764,623 | G/C | — | likely benign |
| rs823156 | 1:205,764,640 | G/A | intron variant | benign |
| rs823157 | 1:205,765,795 | A/T | — | benign |
| rs370322036 | 1:205,766,135 | T/C | — | likely benign |
| rs140660276 | 1:205,766,742 | G/A | intron variant | — |
| rs771097997 | 1:205,767,054 | T/G | — | uncertain significance |
| rs200146515 | 1:205,767,070 | C/T | — | likely benign |
| rs961388605 | 1:205,767,078 | A/C | — | uncertain significance |
| rs560410634 | 1:205,767,104 | C/T | — | uncertain significance |
| rs776783815 | 1:205,767,170 | C/T | — | uncertain significance |
| rs776016676 | 1:205,767,193 | G/T | — | likely benign |
| rs1655802300 | 1:205,767,826 | C/A | — | uncertain significance |
| rs34934230 | 1:205,767,828 | T/A | — | benign |
| rs708727 | 1:205,767,885 | G/A | synonymous variant | benign |
| rs753476016 | 1:205,767,894 | G/A | — | likely benign |
| rs765083575 | 1:205,767,911 | G/A | — | uncertain significance |
| rs758381035 | 1:205,767,937 | A/C | — | uncertain significance |
| rs2102504055 | 1:205,767,943 | C/A | — | pathogenic |
| rs2526638322 | 1:205,768,100 | C/A | — | uncertain significance |
| rs764146152 | 1:205,768,119 | G/A | — | likely benign |
| rs753912617 | 1:205,768,142 | C/T | — | uncertain significance |
| rs772310058 | 1:205,768,147 | G/A | — | uncertain significance |
| rs2526638594 | 1:205,768,159 | T/C | — | uncertain significance |
| rs1303920116 | 1:205,768,164 | A/T | — | uncertain significance |
| rs192760774 | 1:205,768,185 | G/A | — | likely benign |
| rs148572450 | 1:205,768,218 | C/T | — | likely benign |
| rs4396169 | 1:205,768,309 | T/C | — | benign |
| rs756582015 | 1:205,768,918 | C/T | — | uncertain significance |
| rs148096189 | 1:205,770,138 | C/T | — | likely benign |
| rs559222766 | 1:205,770,193 | G/A | — | likely benign |
| rs823075 | 1:205,774,897 | C/T | intron variant | — |
| rs140750630 | 1:205,779,204 | G/A | — | likely benign |
| rs11240569 | 1:205,779,231 | G/A | synonymous variant | benign |
| rs372906697 | 1:205,779,270 | C/A | — | likely benign |
| rs2526666480 | 1:205,779,275 | C/T | — | uncertain significance |
| rs745697767 | 1:205,779,301 | G/A | — | uncertain significance |
| rs200029523 | 1:205,779,318 | G/T | — | likely benign |
| rs369337468 | 1:205,779,334 | A/G | — | uncertain significance |
| rs776123205 | 1:205,779,335 | C/A | — | uncertain significance |
| rs780018493 | 1:205,779,338 | C/T | — | uncertain significance |
| rs2526666835 | 1:205,779,379 | T/A | — | uncertain significance |
| rs1031814971 | 1:205,779,401 | C/T | — | uncertain significance |
| rs776970789 | 1:205,779,402 | G/A | — | likely benign |
| rs1455087665 | 1:205,779,414 | C/A | — | uncertain significance |
| rs2526667032 | 1:205,779,423 | C/G | — | likely benign |
| rs144042954 | 1:205,779,431 | C/A | — | uncertain significance |
| rs767210276 | 1:205,779,442 | T/A | — | uncertain significance |
| rs1656119990 | 1:205,779,470 | C/G | — | uncertain significance |
| rs145968676 | 1:205,779,485 | C/T | — | uncertain significance |
| rs757266827 | 1:205,779,493 | T/A | — | uncertain significance |
| rs746089726 | 1:205,779,501 | G/A | — | likely benign |
| rs142051990 | 1:205,779,542 | C/T | — | uncertain significance |
| rs765974634 | 1:205,779,549 | C/T | — | likely benign |
| rs759228574 | 1:205,779,550 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.