SND1
staphylococcal nuclease and tudor domain containing 1
Summary
This gene encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2), a transcriptional activator that is required for B-lymphocyte transformation. Other transcription factors that interact with this protein are signal transducers and activators of transcription, STATs. This protein is also thought to be essential for normal cell growth. A similar protein in mammals and other organisms is a component of the RNA-induced silencing complex (RISC). [provided by RefSeq, Jul 2016]
Known Variants83 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs73234873 | 7:127,292,004 | C/G | coding sequence variant | — |
| rs73234874 | 7:127,292,021 | G/A | coding sequence variant | — |
| rs145576520 | 7:127,292,442 | G/C | — | likely benign |
| rs940214396 | 7:127,292,447 | G/A | — | uncertain significance |
| rs745495252 | 7:127,292,480 | C/A | — | uncertain significance |
| rs13221709 | 7:127,305,518 | G/A | intron variant | — |
| rs552873253 | 7:127,326,663 | G/A | — | likely benign |
| rs907718518 | 7:127,326,690 | T/A | — | likely benign |
| rs773076395 | 7:127,326,707 | G/A | — | uncertain significance |
| rs567874929 | 7:127,326,717 | T/A | — | likely benign |
| rs144637656 | 7:127,326,782 | C/T | — | uncertain significance |
| rs145331938 | 7:127,326,788 | A/C | missense variant | — |
| rs7783478 | 7:127,328,537 | T/C | intron variant | — |
| rs712716 | 7:127,333,279 | A/G | intron variant | — |
| rs137962837 | 7:127,334,945 | A/G | — | uncertain significance |
| rs775710971 | 7:127,334,947 | G/A | — | likely benign |
| rs751019502 | 7:127,339,006 | A/C | — | uncertain significance |
| rs142740888 | 7:127,341,213 | C/T | — | benign |
| rs777713697 | 7:127,341,242 | T/G | — | uncertain significance |
| rs1446416077 | 7:127,341,294 | G/A | — | uncertain significance |
| rs144027003 | 7:127,341,296 | T/G | — | uncertain significance |
| rs201003399 | 7:127,342,511 | C/T | — | likely benign |
| rs781407519 | 7:127,342,558 | C/T | — | uncertain significance |
| rs373234812 | 7:127,343,289 | T/A | — | uncertain significance |
| rs534570962 | 7:127,343,354 | A/G | — | uncertain significance |
| rs771065505 | 7:127,344,900 | A/G | — | uncertain significance |
| rs144683326 | 7:127,344,910 | G/A | — | likely benign |
| rs2535654130 | 7:127,344,954 | T/G | — | uncertain significance |
| rs748087476 | 7:127,344,968 | C/T | — | uncertain significance |
| rs115701447 | 7:127,344,973 | C/T | — | benign |
| rs199541440 | 7:127,344,974 | G/A | — | uncertain significance |
| rs1796222917 | 7:127,347,640 | G/A | — | uncertain significance |
| rs1242112645 | 7:127,347,681 | G/C | — | uncertain significance |
| rs7778413 | 7:127,357,716 | T/C | regulatory region variant | — |
| rs202087140 | 7:127,361,372 | T/C | — | uncertain significance |
| rs761145782 | 7:127,361,401 | A/G | — | uncertain significance |
| rs567804903 | 7:127,361,440 | G/T | — | uncertain significance |
| rs17151229 | 7:127,382,155 | G/C | intron variant | — |
| rs73234901 | 7:127,398,248 | T/C | — | — |
| rs11536594 | 7:127,406,626 | A/G | intron variant | — |
| rs35940771 | 7:127,430,974 | T/G | regulatory region variant | — |
| rs200994299 | 7:127,484,387 | C/T | — | uncertain significance |
| rs35154268 | 7:127,505,755 | A/C | regulatory region variant | — |
| rs756923362 | 7:127,528,046 | C/A | — | uncertain significance |
| rs3757769 | 7:127,541,062 | A/G | intron variant | — |
| rs144122605 | 7:127,544,817 | A/G | — | uncertain significance |
| rs149773645 | 7:127,544,842 | G/T | — | likely benign |
| rs145473877 | 7:127,544,844 | C/G | — | uncertain significance |
| rs192914914 | 7:127,544,853 | G/A | — | uncertain significance |
| rs72607744 | 7:127,560,541 | G/A | intron variant | — |
| rs9649512 | 7:127,566,637 | G/C | — | — |
| rs2535699461 | 7:127,569,253 | G/A | — | uncertain significance |
| rs2535699468 | 7:127,569,259 | C/G | — | uncertain significance |
| rs60805384 | 7:127,569,261 | G/A | — | benign |
| rs73455713 | 7:127,569,306 | G/A | — | benign |
| rs12154492 | 7:127,584,722 | C/T | intron variant | — |
| rs76805778 | 7:127,593,275 | A/C | — | — |
| rs1802509838 | 7:127,631,024 | G/A | — | uncertain significance |
| rs3735634 | 7:127,672,675 | G/A | regulatory region variant | — |
| rs117123883 | 7:127,682,119 | A/G | intron variant | — |
| rs185455523 | 7:127,683,638 | T/A | intron variant | — |
| rs150626020 | 7:127,690,907 | G/T | intron variant | — |
| rs1428494979 | 7:127,714,603 | G/C | — | uncertain significance |
| rs538568525 | 7:127,714,616 | C/T | — | benign |
| rs144956035 | 7:127,714,617 | G/A | — | likely benign |
| rs796052170 | 7:127,714,645 | A/C | — | likely benign |
| rs542659541 | 7:127,714,649 | C/T | — | likely benign |
| rs1793475434 | 7:127,714,690 | A/G | — | uncertain significance |
| rs2485198730 | 7:127,714,697 | G/A | — | likely benign |
| rs141988056 | 7:127,714,708 | C/G | — | uncertain significance |
| rs1290329046 | 7:127,714,732 | A/T | — | uncertain significance |
| rs78066960 | 7:127,716,892 | G/A | intron variant | — |
| rs1219037625 | 7:127,721,448 | G/A | — | uncertain significance |
| rs929084701 | 7:127,721,495 | C/T | — | likely benign |
| rs2485224299 | 7:127,724,830 | C/T | — | uncertain significance |
| rs745350581 | 7:127,724,886 | G/A | — | uncertain significance |
| rs749124353 | 7:127,725,774 | G/A | — | uncertain significance |
| rs781306917 | 7:127,727,011 | C/T | — | uncertain significance |
| rs201675724 | 7:127,727,068 | G/C | — | uncertain significance |
| rs368551208 | 7:127,729,554 | C/T | — | uncertain significance |
| rs2485235176 | 7:127,729,668 | G/A | — | uncertain significance |
| rs200084233 | 7:127,729,719 | G/A | — | uncertain significance |
| rs539486991 | 7:127,732,105 | C/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.