TRIM31

tripartite motif containing 31

Summary

This gene encodes a protein that functions as an E3 ubiquitin-protein ligase. This gene shows altered expression in certain tumors and may be a negative regulator of cell growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Known Variants46 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs146885411	6:30,071,363	C/A	—	likely benign
rs756360360	6:30,071,395	G/A	—	uncertain significance
rs2534327350	6:30,071,543	G/C	—	uncertain significance
rs17194265	6:30,071,547	C/T	—	benign
rs61745624	6:30,071,562	G/T	—	likely benign
rs1768460953	6:30,071,881	G/A	—	uncertain significance
rs181406164	6:30,072,953	A/G	—	uncertain significance
rs773644902	6:30,072,980	A/T	—	uncertain significance
rs2517664	6:30,073,259	C/T	intron variant	—
rs7767188	6:30,073,776	G/T	—	—
rs2517601	6:30,074,072	G/C	intron variant	—
rs2517600	6:30,074,163	G/T	—	—
rs78026509	6:30,074,310	C/G	intron variant	—
rs7383537	6:30,074,872	C/G	—	—
rs2023473	6:30,075,613	T/C	intron variant	—
rs2023472	6:30,075,864	A/G	synonymous variant	—
rs758082658	6:30,075,908	G/A	—	uncertain significance
rs377565993	6:30,075,944	T/C	—	uncertain significance
rs11961190	6:30,076,117	C/T	intron variant	—
rs9261418	6:30,076,660	G/A	intron variant	—
rs569733107	6:30,076,813	C/T	—	uncertain significance
rs138900010	6:30,078,235	T/G	—	uncertain significance
rs137941449	6:30,078,262	T/C	—	likely benign
rs35775852	6:30,078,265	A/G	—	benign
rs779017353	6:30,078,331	G/A	—	uncertain significance
rs1769197588	6:30,078,338	T/C	—	likely benign
rs749185417	6:30,078,358	T/G	—	uncertain significance
rs1769204391	6:30,078,374	G/T	—	uncertain significance
rs372346318	6:30,078,410	G/A	—	conflicting classifications of pathogenicity
rs369895511	6:30,078,444	T/G	—	conflicting classifications of pathogenicity
rs1485097968	6:30,079,492	A/G	—	uncertain significance
rs147682149	6:30,079,495	A/G	—	uncertain significance
rs376929796	6:30,080,202	A/T	—	uncertain significance
rs34801993	6:30,080,204	T/C	—	benign
rs768959167	6:30,080,255	C/T	—	uncertain significance
rs772682330	6:30,080,265	G/A	—	likely benign
rs35521684	6:30,080,280	C/T	—	benign
rs769703369	6:30,080,285	C/T	—	uncertain significance
rs753447669	6:30,080,307	C/G	—	uncertain significance
rs111260969	6:30,080,311	T/C	—	uncertain significance
rs928628355	6:30,080,323	T/C	—	uncertain significance
rs34704616	6:30,080,369	G/A	missense variant	benign
rs140451451	6:30,080,441	A/G	missense variant	—
rs36063651	6:30,080,533	G/C	—	benign
rs61758092	6:30,080,565	A/C	—	benign
rs368717514	6:30,080,568	C/A	—	conflicting classifications of pathogenicity

Gene information from NCBI Gene. Variant classifications from ClinVar.