TRIM66

tripartite motif containing 66

Summary

Predicted to enable chromatin binding activity; identical protein binding activity; and zinc ion binding activity. Predicted to act upstream of or within negative regulation of DNA-templated transcription. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants100 total

rsidPosition (GRCh37)AllelesClassClinVar
rs1076993111:8,636,105T/G——
rs112855911:8,637,191G/A——
rs1076993311:8,637,926G/C3 prime UTR variant—
rs492992311:8,639,200T/C3 prime UTR variant—
rs492994711:8,639,994G/Cintron variant—
rs78038586711:8,640,352G/A—uncertain significance
rs123736377911:8,640,367G/A—uncertain significance
rs130654315711:8,640,424T/C—uncertain significance
rs98631726811:8,640,510G/C—uncertain significance
rs117863350711:8,641,001G/A—uncertain significance
rs57583225011:8,641,057T/C—uncertain significance
rs98108216611:8,641,079G/A—uncertain significance
rs102109801411:8,641,602G/A—uncertain significance
rs89435526511:8,641,610G/A—uncertain significance
rs133307617411:8,641,637T/C—uncertain significance
rs15012255511:8,642,003T/C—likely benign
rs13844429811:8,642,028A/G—likely benign
rs77052266511:8,642,115C/G—uncertain significance
rs55616827511:8,642,636C/T—likely benign
rs74756480311:8,642,663T/C—uncertain significance
rs254950595711:8,642,709G/C—uncertain significance
rs37243675111:8,642,732C/T—uncertain significance
rs102789199911:8,642,739T/C—uncertain significance
rs139635549411:8,643,254G/C—uncertain significance
rs159200699611:8,643,286G/C—uncertain significance
rs74856007811:8,643,316T/C—uncertain significance
rs75696966811:8,643,322C/T—uncertain significance
rs56056079811:8,643,331C/T—uncertain significance
rs75149822911:8,643,337T/C—uncertain significance
rs254952232411:8,645,920T/C—uncertain significance
rs75540620411:8,645,941G/A—uncertain significance
rs92146164811:8,645,953G/A—uncertain significance
rs95591541111:8,645,956G/A—likely benign
rs138304509611:8,645,957C/T—uncertain significance
rs123296230111:8,645,966G/A—uncertain significance
rs105179654711:8,645,999G/C—uncertain significance
rs130071769711:8,646,297T/C—uncertain significance
rs20222637011:8,646,324C/T—uncertain significance
rs254952479111:8,646,374A/G—likely benign
rs97677143911:8,646,400C/T—uncertain significance
rs55234880211:8,646,408G/T—uncertain significance
rs254952525911:8,646,427C/T—uncertain significance
rs77772442911:8,646,520A/G—uncertain significance
rs76552172311:8,646,535G/A—uncertain significance
rs11504496811:8,646,537C/T—benign
rs7814493411:8,646,605G/A—benign
rs77967858711:8,646,609A/G—uncertain significance
rs77069575911:8,646,627C/T—uncertain significance
rs1104201611:8,647,124C/A——
rs492992511:8,655,187C/Aintron variant—
rs7713159611:8,656,035T/A——
rs254957306911:8,660,317G/T—uncertain significance
rs145966282411:8,661,974T/C—likely benign
rs146917475011:8,662,027T/G—uncertain significance
rs77786462911:8,662,091G/A—uncertain significance
rs144393356611:8,662,099G/A—uncertain significance
rs88741921411:8,662,106G/C—uncertain significance
rs19992163711:8,662,112G/C—uncertain significance
rs75135157711:8,662,259G/C—uncertain significance
rs56027710311:8,662,301C/T—uncertain significance
rs20222900511:8,662,310C/A—uncertain significance
rs101242749011:8,662,313G/C—uncertain significance
rs56794981411:8,662,360C/A—uncertain significance
rs102740010811:8,662,382T/C—uncertain significance
rs90410540511:8,662,448A/G—uncertain significance
rs135956441411:8,662,472G/C—uncertain significance
rs55297545411:8,662,474G/A—uncertain significance
rs19999676911:8,662,501G/A—conflicting classifications of pathogenicity
rs142383076511:8,662,514A/G—uncertain significance
rs1104202311:8,662,516T/Amissense variant—
rs139068906011:8,662,526A/G—uncertain significance
rs55551470311:8,662,546G/A—uncertain significance
rs116528982611:8,662,597A/C—uncertain significance
rs54482209211:8,662,648T/C—uncertain significance
rs88688420711:8,664,597G/C—uncertain significance
rs95308856311:8,667,340T/C—uncertain significance
rs254959688411:8,667,341T/G—uncertain significance
rs76125477411:8,667,373T/G—uncertain significance
rs203679730211:8,667,382A/G—uncertain significance
rs1084009911:8,667,680T/Cintron variant—
rs203685502911:8,668,007A/G—uncertain significance
rs6174277011:8,668,016T/G—benign
rs146630374711:8,668,040A/G—uncertain significance
rs7848276011:8,669,510G/A—benign
rs103904006811:8,669,562T/G—uncertain significance
rs254960557611:8,670,056G/A—uncertain significance
rs124401872411:8,670,068G/A—uncertain significance
rs93655845711:8,670,078C/T—uncertain significance
rs134716286711:8,671,307C/G—uncertain significance
rs125022560611:8,671,356T/C—uncertain significance
rs75920850911:8,671,413T/C—uncertain significance
rs140352666111:8,671,433T/C—uncertain significance
rs425698011:8,673,939C/A——
rs1084010211:8,676,238C/Tintron variant—
rs794151011:8,677,063C/G——
rs795052811:8,677,185T/A——
rs711052911:8,687,710C/A——
rs1104202911:8,688,125C/T——
rs1227147011:8,691,012G/Aintron variant—
rs1257525211:8,694,073G/Cupstream gene variant—

Gene information from NCBI Gene. Variant classifications from ClinVar.