rs10888682
This variant is located in the MACF1 gene.
▶GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
total lipids in large HDL
cholesteryl esters in large HDL measurement
total cholesterol change measurement, high density lipoprotein cholesterol measurement
free cholesterol in large HDL measurement
apolipoprotein A 1 measurement
phospholipids in very large HDL measurement
free cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement
high density lipoprotein cholesterol measurement
total cholesterol measurement, high density lipoprotein cholesterol measurement
About MACF1
This gene encodes a large protein containing numerous spectrin and leucine-rich repeat (LRR) domains. The encoded protein is a member of a family of proteins that form bridges between different cytoskeletal elements. This protein facilitates actin-microtubule interactions at the cell periphery and couples the microtubule network to cellular junctions. Alternative splicing results in multiple transcript variants, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, May 2013]
View all MACF1 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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