rs1808192

GWAS Catalog Trait Associations (12)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

sex hormone-binding globulin measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.03
p 1.0e-23
N 322,484
Major Consortium StudyLarge GWAS
multi-ancestry

level of serum globulin type protein

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.03
p 1.0e-22
N 325,292
Major Consortium StudyLarge GWAS
multi-ancestry

apolipoprotein B measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.02
p 2.0e-20
N 354,097
Major Consortium StudyLarge GWAS
multi-ancestry

blood protein amount

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.02
p 4.0e-20
N 325,292
Major Consortium StudyLarge GWAS
multi-ancestry

low density lipoprotein cholesterol measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.02
p 4.0e-19
N 355,197
Major Consortium StudyLarge GWAS
multi-ancestry

total cholesterol measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.02
p 3.0e-16
N 355,858
Major Consortium StudyLarge GWAS
multi-ancestry

body mass index

Huang J et al. Genomics and phenomics of body mass index reveals a complex disease network. Nature Communications 13(1):7973 (2022)
Allele G
OR 0.01
p 7.0e-13
N 1,122,049
Large GWAS
European
Koskeridis F et al. Pleiotropic genetic architecture and novel loci for C-reactive protein levels. Nature Communications 13(1):6939 (2022)
Allele G
OR 0.01
p 4.0e-8
N 694,649
Large GWAS
European
Allele G
OR
β 0.016
p 6.0e-9
N 334,487
Large GWAS
multi-ancestry

interleukin-5 receptor subunit alpha measurement

Allele G
OR 0.04
p 7.0e-13
N 47,745
Large GWAS
European

blood phosphate measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.02
p 4.0e-11
N 325,141
Major Consortium StudyLarge GWAS
multi-ancestry

hypothyroidism

Figuerêdo J et al. Uncovering the shared genetic components of thyroid disorders and reproductive health. European Journal of Endocrinology 191(2):211-222 (2024)
Allele A
OR 1.05
p 5.0e-11
N 691,986
Large GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

Community Wiki

No community notes yet for this variant. Sign in to start one.

Comments

Sign in to join the discussion.

Loading comments…