rs2049865
▶GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
phosphoglycerides measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 8.0e-27
N 450,015
Large GWAS
multi-ancestry
free cholesterol in small HDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 6.0e-20
N 450,015
Large GWAS
multi-ancestry
phospholipids in small HDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.02
p 1.0e-16
N 450,015
Large GWAS
multi-ancestry
low density lipoprotein cholesterol measurement
Koskeridis F et al. “Pleiotropic genetic architecture and novel loci for C-reactive protein levels.” Nature Communications 13(1):6939 (2022)
Allele A
OR 0.01
p 4.0e-16
N 361,194
Large GWAS
European
leptin receptor measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.04
p 2.0e-13
N 47,745
Large GWAS
European
total lipids in small HDL measurement
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele A
OR 0.01
p 1.0e-11
N 450,015
Large GWAS
multi-ancestry
digestive system disease, abdominal abscess
Tängdén T et al. “A genome-wide association study in a large community-based cohort identifies multiple loci associated with susceptibility to bacterial and viral infections.” Scientific Reports 12(1):2582 (2022)
Allele C
OR 0.95
p 5.0e-10
N 337,484
Large GWAS
European
skin pigmentation
Vollenbrock CE et al. “Genome-wide association study identifies novel loci associated with skin autofluorescence in individuals without diabetes.” Bmc Genomics 23(1):840 (2022)
Allele A
OR 0.00
p 9.0e-10
N 27,254
Large GWAS
European
diverticular disease
Maguire LH et al. “Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease.” Nature Genetics 50(10):1359-1365 (2018)
Allele A
OR —
β 0.003
p 6.0e-9
N 409,728
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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