rs34333163

GWAS Catalog Trait Associations (12)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

high density lipoprotein cholesterol measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.07
p 1.0e-47
N 325,634
Major Consortium StudyLarge GWAS
multi-ancestry

white matter volume measurement, cerebellar volume measurement

Primus SA et al. Beyond volume: Unraveling the genetics of human brain geometry. Science Advances 11(24):eadr1644 (2025)
Allele G
OR
p 1.0e-44
N 19,862
Large GWAS
European

apolipoprotein A 1 measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.06
p 2.0e-38
N 323,833
Major Consortium StudyLarge GWAS
multi-ancestry

aspartate aminotransferase measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.05
p 2.0e-24
N 354,541
Major Consortium StudyLarge GWAS
multi-ancestry

total cholesterol measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.05
p 6.0e-24
N 355,858
Major Consortium StudyLarge GWAS
multi-ancestry

calcium measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.05
p 2.0e-21
N 325,659
Major Consortium StudyLarge GWAS
multi-ancestry

substance-related disorder

Allele A
OR 8.79
p 2.0e-18
N 1,517,369
Large GWAS
multi-ancestry

serum albumin amount

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele G
OR 0.04
p 2.0e-17
N 325,292
Major Consortium StudyLarge GWAS
multi-ancestry

fat pad mass

Harris BHL et al. New role of fat-free mass in cancer risk linked with genetic predisposition. Scientific Reports 14(1):7270 (2024)
Allele G
OR 0.04
p 2.0e-14
N 337,196
Large GWAS
European

insomnia

Allele A
OR 0.01
p 3.0e-14
N 2,365,010
Meta-analysisLarge GWAS
European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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