rs4128744
▶GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
free cholesterol to total lipids in chylomicrons and extremely large VLDL percentage
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.06
p 1.0e-45
N 203,300
Large GWAS
European
metabolic syndrome
Ho CY et al. “A Genome-Wide Association Study of Metabolic Syndrome in the Taiwanese Population.” Nutrients 16(1) (2023)
Allele C
OR 0.15
p 3.0e-17
N 107,230
Large GWAS
East Asian
total lipids in large LDL
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 1.0e-12
N 450,015
Large GWAS
multi-ancestry
triglyceride measurement
Bandesh K et al. “Genome-wide association study of blood lipids in Indians confirms universality of established variants.” Journal of Human Genetics 64(6):573-587 (2019)
Allele A
OR 13.59
p 2.0e-9
N 1,036
Large GWAS
multi-ancestry
high density lipoprotein cholesterol measurement
Bandesh K et al. “Genome-wide association study of blood lipids in Indians confirms universality of established variants.” Journal of Human Genetics 64(6):573-587 (2019)
Allele A
OR 2.21
p 3.0e-9
N 1,036
Large GWAS
multi-ancestry
fatty acid amount
Sun Y et al. “GWAS and multi-omics integrative analysis reveal novel loci and their molecular mechanisms for circulating fatty acids.” Hgg Advances 6(4):100470 (2025)
Allele T
OR —
p 3.0e-8
N 110,346
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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