Trait
SNPs associated with total lipids in large LDL
221 genetic variants across 78 genes have been associated with total lipids in large LDL in published research. Key genes include ABCA6, ABCB11, ABCG5.
Associated variants221 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1065853 | — | GWAS association (p=0.0e+00) | Large GWAS |
| rs183130 | CETP | GWAS association (p=0.0e+00) | Large GWAS |
| rs2070895 | LIPC | GWAS association (p=0.0e+00) | Large GWAS |
| rs964184 | APOA5 | GWAS association (p=0.0e+00) | Large GWAS |
| rs7412 | APOE | GWAS association (p=0.0e+00) | Large GWAS |
| rs11591147 | PCSK9 | GWAS association (p=6.0e-210) | Large GWAS |
| rs73015024 | — | GWAS association (p=5.0e-207) | Large GWAS |
| rs12740374 | CELSR2 | GWAS association (p=6.0e-207) | Large GWAS |
| rs646776 | CELSR2 | GWAS association (p=9.0e-201) | Large GWAS |
| rs118147862 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs7254892 | — | GWAS association (p=1.0e-200) | Large GWAS |
| rs581411 | — | GWAS association (p=4.0e-198) | Large GWAS |
| rs3812316 | MLXIPL | GWAS association (p=6.0e-196) | Large GWAS |
| rs686030 | TTC39B | GWAS association (p=1.0e-158) | Large GWAS |
| rs15285 | LPL | GWAS association (p=3.0e-146) | Large GWAS |
| rs563290 | — | GWAS association (p=3.0e-146) | Large GWAS |
| rs2740488 | — | GWAS association (p=1.0e-145) | Large GWAS |
| rs10184054 | — | GWAS association (p=3.0e-137) | Large GWAS |
| rs102275 | TMEM258 | GWAS association (p=8.0e-112) | Large GWAS |
| rs28601761 | — | GWAS association (p=6.0e-105) | Large GWAS |
| rs12151108 | — | GWAS association (p=3.0e-95) | Large GWAS |
| rs4986970 | LCAT | GWAS association (p=4.0e-83) | Large GWAS |
| rs12916 | HMGCR | GWAS association (p=2.0e-82) | Large GWAS |
| rs6065908 | PCIF1 | GWAS association (p=9.0e-78) | Large GWAS |
| rs3846662 | HMGCR | GWAS association (p=2.0e-77) | Large GWAS |
| rs562338 | — | GWAS association (p=6.0e-74) | Large GWAS |
| rs35980001 | — | GWAS association (p=6.0e-74) | Large GWAS |
| rs7177289 | — | GWAS association (p=4.0e-69) | Large GWAS |
| rs17315646 | GALNT2 | GWAS association (p=5.0e-55) | Large GWAS |
| rs2900478 | SLCO1B1 | GWAS association (p=1.0e-53) | Large GWAS |
| rs139974673 | — | GWAS association (p=1.0e-52) | Large GWAS |
| rs4704834 | — | GWAS association (p=1.0e-50) | Large GWAS |
| rs12750160 | USP24 | GWAS association (p=2.0e-49) | Large GWAS |
| rs3129770 | — | GWAS association (p=3.0e-45) | Large GWAS |
| rs181948526 | — | GWAS association (p=3.0e-45) | Large GWAS |
| rs635634 | — | GWAS association (p=5.0e-45) | Large GWAS |
| rs2519093 | ABO | GWAS association (p=3.0e-43) | Large GWAS |
| rs11887534 | ABCG5 | GWAS association (p=2.0e-42) | Large GWAS |
| rs1229984 | ADH1B | GWAS association (p=2.0e-42) | Large GWAS |
| rs597808 | ATXN2 | GWAS association (p=6.0e-42) | Large GWAS |
| rs174574 | FADS2 | GWAS association (p=1.0e-41) | Large GWAS |
| rs73001065 | — | GWAS association (p=2.0e-41) | Large GWAS |
| rs4245791 | ABCG8 | GWAS association (p=4.0e-41) | Large GWAS |
| rs11751024 | — | GWAS association (p=2.0e-32) | Large GWAS |
| rs557933 | — | GWAS association (p=3.0e-32) | Large GWAS |
| rs4656292 | — | GWAS association (p=1.0e-31) | Large GWAS |
| rs1935 | JMJD1C | GWAS association (p=8.0e-31) | Large GWAS |
| rs112875651 | — | GWAS association (p=9.0e-31) | Large GWAS |
| rs11749783 | — | GWAS association (p=2.0e-30) | Large GWAS |
| rs56325564 | — | GWAS association (p=3.0e-30) | Large GWAS |
| rs117113213 | — | GWAS association (p=3.0e-30) | Large GWAS |
| rs556107 | — | GWAS association (p=7.0e-30) | Large GWAS |
| rs147711004 | — | GWAS association (p=8.0e-29) | Large GWAS |
| rs782134971 | — | GWAS association (p=1.0e-28) | Large GWAS |
| rs72926946 | — | GWAS association (p=5.0e-27) | Large GWAS |
| rs115478735 | ABO | GWAS association (p=8.0e-27) | Large GWAS |
| rs9987289 | LOC157273 | GWAS association (p=1.0e-26) | Large GWAS |
| rs881844 | STARD3 | GWAS association (p=3.0e-26) | Large GWAS |
| rs261290 | — | GWAS association (p=6.0e-26) | Large GWAS |
| rs118170342 | — | GWAS association (p=2.0e-25) | Large GWAS |
| rs114165349 | — | GWAS association (p=9.0e-25) | Large GWAS |
| rs12208357 | SLC22A1 | GWAS association (p=1.0e-24) | Large GWAS |
| rs2287997 | — | GWAS association (p=3.0e-24) | Large GWAS |
| rs6475606 | CDKN2B-AS1 | GWAS association (p=4.0e-24) | Large GWAS |
| rs525028 | — | GWAS association (p=7.0e-24) | Large GWAS |
| rs73066485 | — | GWAS association (p=3.0e-23) | Large GWAS |
| rs77542162 | ABCA6 | GWAS association (p=5.0e-23) | Large GWAS |
| rs484084 | — | GWAS association (p=6.0e-23) | Large GWAS |
| rs4307732 | — | GWAS association (p=3.0e-22) | Large GWAS |
| rs75608688 | ETV5 | GWAS association (p=4.0e-22) | Large GWAS |
| rs2618566 | — | GWAS association (p=5.0e-22) | Large GWAS |
| rs58198139 | — | GWAS association (p=6.0e-22) | Large GWAS |
| rs115849089 | — | GWAS association (p=8.0e-22) | Large GWAS |
| rs4738680 | — | GWAS association (p=1.0e-21) | Large GWAS |
| rs738408 | PNPLA3 | GWAS association (p=1.0e-21) | Large GWAS |
| rs1007205 | — | GWAS association (p=1.0e-21) | Large GWAS |
| rs4299376 | ABCG8 | GWAS association (p=3.0e-21) | Large GWAS |
| rs7313056 | MYO1H | GWAS association (p=4.0e-21) | Large GWAS |
| rs142385484 | — | GWAS association (p=5.0e-21) | Large GWAS |
| rs6073958 | — | GWAS association (p=5.0e-21) | Large GWAS |
| rs11394256 | — | GWAS association (p=2.0e-20) | Large GWAS |
| rs2866372 | — | GWAS association (p=2.0e-20) | Large GWAS |
| rs921919 | SCARB1 | GWAS association (p=4.0e-20) | Large GWAS |
| rs41279633 | — | GWAS association (p=4.0e-20) | Large GWAS |
| rs6882345 | — | GWAS association (p=6.0e-20) | Large GWAS |
| rs11636917 | — | GWAS association (p=9.0e-20) | Large GWAS |
| rs62275881 | — | GWAS association (p=1.0e-19) | Large GWAS |
| rs62168795 | R3HDM1 | GWAS association (p=2.0e-19) | Large GWAS |
| rs2332969 | — | GWAS association (p=2.0e-19) | Large GWAS |
| rs73544366 | — | GWAS association (p=3.0e-19) | Large GWAS |
| rs28929474 | SERPINA1 | GWAS association (p=4.0e-19) | Large GWAS |
| rs479844 | — | GWAS association (p=1.0e-18) | Large GWAS |
| rs632016 | — | GWAS association (p=1.0e-18) | Large GWAS |
| rs150169808 | — | GWAS association (p=1.0e-18) | Large GWAS |
| rs705379 | PON1 | GWAS association (p=2.0e-18) | Large GWAS |
| rs998584 | POLR1C | GWAS association (p=2.0e-18) | Large GWAS |
| rs80254170 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs60146811 | — | GWAS association (p=6.0e-18) | Large GWAS |
| rs771193934 | — | GWAS association (p=1.0e-17) | Large GWAS |
| rs79598313 | — | GWAS association (p=1.0e-17) | Large GWAS |
Showing the top 100 of 221 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.