TTC39B

tetratricopeptide repeat domain 39B

Summary

Predicted to be involved in several processes, including cholesterol homeostasis; negative regulation of cholesterol storage; and regulation of cholesterol efflux. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants73 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs562062700	9:15,169,299	C/A	—	—
rs80279305	9:15,175,039	T/C	—	benign
rs1250744589	9:15,175,064	T/A	—	uncertain significance
rs778519863	9:15,175,069	A/G	—	uncertain significance
rs138535620	9:15,175,098	G/A	—	uncertain significance
rs77494837	9:15,177,718	T/C	—	benign
rs377291867	9:15,177,748	C/A	—	uncertain significance
rs781381791	9:15,182,370	C/A	—	uncertain significance
rs1237197775	9:15,182,401	C/G	—	uncertain significance
rs770409139	9:15,185,327	C/T	—	uncertain significance
rs140567902	9:15,185,330	C/T	—	uncertain significance
rs1329208960	9:15,185,361	G/A	—	uncertain significance
rs1287444625	9:15,186,960	T/C	—	uncertain significance
rs2540476218	9:15,186,975	A/C	—	uncertain significance
rs2540476228	9:15,186,976	C/A	—	uncertain significance
rs754552403	9:15,186,991	G/A	—	uncertain significance
rs112186053	9:15,187,010	T/C	—	benign
rs150371121	9:15,188,018	T/C	—	uncertain significance
rs1333500822	9:15,188,028	T/A	—	uncertain significance
rs375535482	9:15,189,601	T/C	—	uncertain significance
rs137958437	9:15,189,607	C/A	—	uncertain significance
rs764580860	9:15,189,627	G/A	—	uncertain significance
rs80193490	9:15,189,719	G/A	—	benign
rs2540491943	9:15,189,742	A/G	—	uncertain significance
rs61755267	9:15,189,757	C/T	—	uncertain significance
rs1399584752	9:15,190,569	T/A	—	uncertain significance
rs758648195	9:15,190,638	C/T	—	uncertain significance
rs771858073	9:15,191,207	A/G	—	uncertain significance
rs74818741	9:15,191,209	A/G	—	benign
rs369656858	9:15,191,235	C/G	—	uncertain significance
rs778037562	9:15,192,622	C/G	—	uncertain significance
rs150826220	9:15,192,688	C/G	—	uncertain significance
rs552439269	9:15,199,878	T/C	—	uncertain significance
rs773256838	9:15,203,825	A/C	—	uncertain significance
rs762726772	9:15,210,150	T/G	—	uncertain significance
rs369032856	9:15,211,273	G/A	—	uncertain significance
rs1323787504	9:15,211,279	A/G	—	uncertain significance
rs757809582	9:15,211,295	C/A	—	uncertain significance
rs143424497	9:15,211,342	T/C	—	uncertain significance
rs1200278174	9:15,211,363	T/C	—	uncertain significance
rs150935312	9:15,211,380	C/T	—	uncertain significance
rs1820192111	9:15,211,384	C/T	—	uncertain significance
rs372085656	9:15,214,159	C/T	—	uncertain significance
rs75713085	9:15,214,193	T/C	—	likely benign
rs10961917	9:15,214,237	G/T	—	likely benign
rs371470245	9:15,214,255	T/C	—	likely benign
rs1821097230	9:15,225,918	C/G	—	uncertain significance
rs149539773	9:15,225,936	C/T	—	likely benign
rs199947112	9:15,225,937	G/A	—	uncertain significance
rs75681700	9:15,225,947	C/T	—	benign
rs72700653	9:15,249,050	T/C	—	benign
rs7874043	9:15,249,431	C/A	—	benign
rs7860457	9:15,258,764	A/T	—	—
rs754168316	9:15,267,937	C/G	—	uncertain significance
rs12348997	9:15,273,466	A/G	intron variant	—
rs12003180	9:15,283,097	C/T	intron variant	—
rs535772	9:15,285,670	A/T	—	—
rs471364	9:15,289,578	C/T	intron variant	—
rs486349	9:15,293,116	G/C	—	—
rs540885	9:15,294,596	G/A	intron variant	—
rs570524	9:15,295,483	C/T	intron variant	—
rs643531	9:15,296,034	C/G	—	—
rs677622	9:15,302,613	A/T	—	—
rs686030	9:15,304,782	C/A	regulatory region variant	—
rs581080	9:15,305,378	G/C	intron variant	—
rs764638288	9:15,307,195	G/C	—	uncertain significance
rs146201898	9:15,307,197	C/T	—	uncertain significance
rs1470175182	9:15,307,207	C/A	—	uncertain significance
rs2540925770	9:15,307,227	G/A	—	uncertain significance
rs530623424	9:15,307,228	A/G	—	likely benign
rs200297100	9:15,307,246	C/G	—	uncertain significance
rs1410964835	9:15,307,249	G/C	—	uncertain significance
rs895362992	9:15,307,269	G/T	—	uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.