rs7207400

This is a intron variant variant in the LINC02210-CRHR1 gene.

GWAS Catalog Trait Associations (12)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

phospholipids in large HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 2.0e-19
N 450,015
Large GWAS
multi-ancestry

HDL particle size

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 5.0e-19
N 450,015
Large GWAS
multi-ancestry

total lipids in large HDL

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 3.0e-18
N 450,015
Large GWAS
multi-ancestry

phospholipids:total lipids ratio

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 7.0e-17
N 450,015
Large GWAS
multi-ancestry

concentration of large HDL particles measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 1.0e-16
N 450,015
Large GWAS
multi-ancestry

free cholesterol in large HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 3.0e-16
N 450,015
Large GWAS
multi-ancestry

cholesterol in large HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 4.0e-16
N 450,015
Large GWAS
multi-ancestry

cholesteryl esters in large HDL measurement

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.02
p 7.0e-16
N 450,015
Large GWAS
multi-ancestry

Anxiety

Allele C
OR 0.02
p 2.0e-15
N 348,219
Meta-analysisLarge GWAS
European

free cholesterol to total lipids in very large HDL percentage

Zoodsma M et al. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 57(10):2445-2455 (2025)
Allele C
OR 0.01
p 6.0e-13
N 450,015
Large GWAS
multi-ancestry

About LINC02210-CRHR1

This locus represents naturally occurring readthrough transcription between neighboring genes CRHR1-IT1, CRHR1 intronic transcript 1 (Gene ID: 147081) and CRHR1, corticotropin releasing hormone receptor 1 (Gene ID: 1394) on chromosome 17. The readthrough transcript encodes a protein that shares sequence identity with the product of the CRHR1 gene. [provided by RefSeq, Dec 2016]

View all LINC02210-CRHR1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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