rs799157

GWAS Catalog Trait Associations (20)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

triglyceride measurement

Allele C
OR 0.08
p 1.0e-68
N 394,642
Large GWAS
European
Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele C
OR 0.09
p 3.0e-57
N 355,577
Major Consortium StudyLarge GWAS
multi-ancestry

triglyceride:HDL cholesterol ratio

Allele T
OR 0.11
p 3.0e-43
N 402,398
Major Consortium StudyLarge GWAS
European

non-high density lipoprotein cholesterol measurement

Allele C
OR 0.06
p 2.0e-33
N 1,320,016
Large GWAS
European

apolipoprotein B measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele C
OR 0.06
p 1.0e-27
N 354,097
Major Consortium StudyLarge GWAS
multi-ancestry

total cholesterol measurement

Allele C
OR 0.04
p 2.0e-20
N 1,320,016
Large GWAS
European
Allele C
OR 0.03
p 4.0e-8
N 928,679
Large GWAS
multi-ancestry
Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele C
OR 0.05
p 6.0e-16
N 355,858
Major Consortium StudyLarge GWAS
multi-ancestry

alkaline phosphatase measurement

Allele T
OR 0.00
p 3.0e-20
N 437,438
Large GWAS
European
Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.04
p 4.0e-13
N 355,891
Major Consortium StudyLarge GWAS
multi-ancestry

low density lipoprotein cholesterol measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele C
OR 0.05
p 9.0e-17
N 355,197
Major Consortium StudyLarge GWAS
multi-ancestry
Allele C
OR 0.03
p 1.0e-12
N 1,320,016
Large GWAS
European

aspartate aminotransferase to alanine aminotransferase ratio

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele C
OR 0.05
p 7.0e-16
N 354,455
Major Consortium StudyLarge GWAS
multi-ancestry

remnant cholesterol measurement

Karjalainen MK et al. Genome-wide characterization of circulating metabolic biomarkers. Nature 628(8006):130-138 (2024)
Allele T
OR 0.08
p 4.0e-12
N 136,016
Large GWAS
multi-ancestry

high density lipoprotein cholesterol measurement

Sinnott-Armstrong N et al. Genetics of 35 blood and urine biomarkers in the UK Biobank. Nature Genetics 53(2):185-194 (2021)
Allele C
OR 0.04
p 7.0e-12
N 325,634
Major Consortium StudyLarge GWAS
multi-ancestry

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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