rs9275572
This is a upstream gene variant variant.
▶GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (5)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
alopecia areata
Petukhova L et al. “Genome-wide association study in alopecia areata implicates both innate and adaptive immunity.” Nature 466(7302):113-7 (2010)
Allele G
OR 2.21
p 1.0e-35
N 4,332
Large GWAS
European
chronic hepatitis C virus infection
Miki D et al. “HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.” Plos One 8(12):e84226 (2013)
Allele T
OR 1.27
p 4.0e-16
N 3,444
Large GWAS
East Asian
systemic lupus erythematosus
Armstrong DL et al. “GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region.” Genes and Immunity 15(6):347-54 (2014)
Allele A
OR 1.74
p 5.0e-16
N 3,163
Large GWAS
European
hepatocellular carcinoma
Kumar V et al. “Genome-wide association study identifies a susceptibility locus for HCV-induced hepatocellular carcinoma.” Nature Genetics 43(5):455-8 (2011)
Allele A
OR 1.30
p 6.0e-9
N 3,611
Large GWAS
East Asian
Henoch-Schoenlein purpura
Koskela M et al. “HLA-DQ and HLA-DRB1 alleles associated with Henoch-Schönlein purpura nephritis in Finnish pediatric population: a genome-wide association study.” Pediatric Nephrology (berlin, Germany) 36(8):2311-2318 (2021)
Allele A
OR 0.17
p 8.0e-9
N 18,803
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
Community Wiki
No community notes yet for this variant. Sign in to start one.
Comments
Sign in to join the discussion.
Loading comments…