Trait
SNPs associated with chronic hepatitis C virus infection
14 genetic variants across 6 genes have been associated with chronic hepatitis C virus infection in published research. Key genes include DEPDC5, HLA-B, IFNL3.
Associated variants14 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs7270101 | ITPA | GWAS association (p=9.0e-76) | Large GWAS |
| rs1127354 | ITPA | GWAS association (p=2.0e-58) | Large GWAS |
| rs8099917 | IFNL3 | GWAS association (p=3.0e-32) | Large GWAS |
| rs12979860 | IFNL4 | GWAS association (p=1.0e-28) | Large GWAS |
| rs8113007 | — | GWAS association (p=7.0e-28) | Large GWAS |
| rs4803217 | IFNL3 | GWAS association (p=1.0e-22) | Large GWAS |
| rs9275572 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs9275263 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs9275267 | — | GWAS association (p=3.0e-12) | Large GWAS |
| rs2853968 | MICA | GWAS association (p=2.0e-10) | Large GWAS |
| rs709053 | HLA-B | GWAS association (p=2.0e-09) | Large GWAS |
| rs1012068 | DEPDC5 | GWAS association (p=1.0e-13) | Small GWAS |
| rs11697186 | ITPA | GWAS association (p=9.0e-25) | Small GWAS |
| rs6139030 | ITPA | GWAS association (p=2.0e-25) | Small GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.