Trait
SNPs associated with Abdominal Aortic Aneurysm
54 genetic variants across 17 genes have been associated with Abdominal Aortic Aneurysm in published research. Key genes include APOA5, APOE, CDKN1A.
Associated variants54 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2891168 | CDKN2B-AS1 | GWAS association (p=8.0e-35) | Meta-analysis |
| rs10757274 | CDKN2B-AS1 | Higher risk of abdominal aortic aneurysm | Meta-analysis |
| rs7025486 | DAB2IP | Higher aortic aneurysm risk | Meta-analysis |
| rs10455872 | LPA | GWAS association (p=3.0e-22) | Meta-analysis |
| rs12740374 | CELSR2 | GWAS association (p=1.0e-18) | Meta-analysis |
| rs58749629 | — | GWAS association (p=2.0e-17) | Meta-analysis |
| rs143235478 | — | GWAS association (p=7.0e-17) | Meta-analysis |
| rs11172113 | LRP1 | GWAS association (p=5.0e-15) | Meta-analysis |
| rs6511720 | LDLR | GWAS association (p=8.0e-14) | Meta-analysis |
| rs58365910 | — | GWAS association (p=1.0e-13) | Meta-analysis |
| rs12133641 | IL6R | GWAS association (p=5.0e-13) | Meta-analysis |
| rs12869493 | — | GWAS association (p=6.0e-13) | Meta-analysis |
| rs10985349 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs1795061 | — | GWAS association (p=9.0e-11) | Meta-analysis |
| rs34316398 | — | GWAS association (p=1.0e-10) | Meta-analysis |
| rs9316871 | — | GWAS association (p=5.0e-10) | Meta-analysis |
| rs662799 | APOA5 | GWAS association (p=8.0e-10) | Meta-analysis |
| rs2836411 | ERG | GWAS association (p=6.0e-09) | Meta-analysis |
| rs602633 | — | GWAS association (p=7.0e-09) | Meta-analysis |
| rs1660371 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs5900493 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs534570261 | SSBP3 | GWAS association (p=3.0e-08) | Meta-analysis |
| rs4977574 | CDKN2B-AS1 | GWAS association (p=1.0e-50) | Major Consortium Study |
| rs389877 | — | GWAS association (p=2.0e-25) | Major Consortium Study |
| rs429358 | APOE | GWAS association (p=9.0e-23) | Major Consortium Study |
| rs12857403 | — | GWAS association (p=4.0e-21) | Major Consortium Study |
| rs964184 | APOA5 | GWAS association (p=2.0e-20) | Major Consortium Study |
| rs4936098 | — | GWAS association (p=4.0e-19) | Major Consortium Study |
| rs7528419 | CELSR2 | GWAS association (p=2.0e-18) | Major Consortium Study |
| rs4970836 | PSRC1 | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs4800133 | LOC124904262 | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs118039278 | LPA | GWAS association (p=4.0e-18) | Major Consortium Study |
| rs4129267 | IL6R | GWAS association (p=6.0e-17) | Major Consortium Study |
| rs1892971 | — | GWAS association (p=7.0e-17) | Major Consortium Study |
| rs17486278 | CHRNA5 | GWAS association (p=4.0e-16) | Major Consortium Study |
| rs138294113 | — | GWAS association (p=7.0e-16) | Major Consortium Study |
| rs1412445 | LIPA | GWAS association (p=5.0e-15) | Major Consortium Study |
| rs4401144 | — | GWAS association (p=4.0e-14) | Major Consortium Study |
| rs55958997 | — | GWAS association (p=9.0e-14) | Major Consortium Study |
| rs2689691 | — | GWAS association (p=2.0e-13) | Major Consortium Study |
| rs1106370 | — | GWAS association (p=1.0e-12) | Major Consortium Study |
| rs4760 | — | GWAS association (p=5.0e-12) | Major Consortium Study |
| rs1412444 | LIPA | GWAS association (p=3.0e-11) | Major Consortium Study |
| rs10985343 | — | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs11591147 | PCSK9 | GWAS association (p=6.0e-11) | Major Consortium Study |
| rs3176336 | CDKN1A | GWAS association (p=1.0e-10) | Major Consortium Study |
| rs10808546 | — | GWAS association (p=1.0e-10) | Major Consortium Study |
| rs73149487 | — | GWAS association (p=8.0e-09) | Major Consortium Study |
| rs10023907 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs35254673 | — | GWAS association (p=3.0e-08) | Major Consortium Study |
| rs7255 | — | GWAS association (p=1.0e-14) | Major Consortium Study |
| rs10757278 | CDKN2B-AS1 | Increased risk of abdominal aortic aneurysm | Large GWAS |
| rs1466535 | LRP1 | GWAS association (p=5.0e-10) | Large GWAS |
| rs2383207 | CDKN2B-AS1 | GWAS association (p=2.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.